Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   ES298_RS10070 Genome accession   NZ_CP038253
Coordinates   1943426..1944379 (-) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain TVO_1901929     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1938426..1949379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES298_RS10045 (ES298_10585) - 1939187..1939810 (-) 624 WP_000932658.1 hypothetical protein -
  ES298_RS10050 (ES298_10590) jag 1939861..1940847 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  ES298_RS10055 (ES298_10595) - 1940866..1941690 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  ES298_RS10060 (ES298_10600) rnpA 1941665..1942036 (-) 372 WP_000739246.1 ribonuclease P protein component -
  ES298_RS11215 - 1942053..1942184 (-) 132 WP_000768904.1 hypothetical protein -
  ES298_RS10065 (ES298_10605) - 1942185..1943375 (-) 1191 WP_000167765.1 acetate kinase -
  ES298_RS10070 (ES298_10610) comYH 1943426..1944379 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  ES298_RS10075 (ES298_10615) - 1944440..1945032 (-) 593 Protein_1983 class I SAM-dependent methyltransferase -
  ES298_RS10080 (ES298_10620) comGG/cglG 1945135..1945581 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  ES298_RS10085 (ES298_10625) comGF/cglF 1945559..1946020 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  ES298_RS10090 (ES298_10630) comGE/cglE 1945983..1946285 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  ES298_RS10095 (ES298_10635) comGD/cglD 1946248..1946682 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  ES298_RS10100 (ES298_10640) comGC/cglC 1946645..1946968 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  ES298_RS10105 (ES298_10645) comGB/cglB 1946970..1947986 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  ES298_RS10110 (ES298_10650) comGA/cglA/cilD 1947934..1948875 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  ES298_RS10115 (ES298_10655) - 1948951..1949316 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=352733 ES298_RS10070 WP_000345126.1 1943426..1944379(-) (comYH) [Streptococcus pneumoniae strain TVO_1901929]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=352733 ES298_RS10070 WP_000345126.1 1943426..1944379(-) (comYH) [Streptococcus pneumoniae strain TVO_1901929]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment