Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ES276_RS08310 Genome accession   NZ_CP038252
Coordinates   1633495..1634232 (-) Length   245 a.a.
NCBI ID   WP_000782664.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901936     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1628495..1639232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES276_RS08290 (ES276_08820) msrB 1629998..1630936 (-) 939 WP_000818207.1 peptide-methionine (R)-S-oxide reductase MsrB -
  ES276_RS08295 - 1630965..1631111 (-) 147 WP_057599590.1 hypothetical protein -
  ES276_RS08300 (ES276_08825) thrB 1631187..1632056 (-) 870 WP_000692438.1 homoserine kinase -
  ES276_RS08305 (ES276_08830) - 1632058..1633344 (-) 1287 WP_000216382.1 homoserine dehydrogenase -
  ES276_RS08310 (ES276_08835) mecA 1633495..1634232 (-) 738 WP_000782664.1 adaptor protein MecA Regulator
  ES276_RS08315 (ES276_08840) - 1634432..1635466 (-) 1035 WP_000461502.1 hypothetical protein -
  ES276_RS08320 (ES276_08845) - 1635495..1636928 (-) 1434 WP_000565078.1 O-antigen polysaccharide polymerase Wzy family protein -
  ES276_RS08325 (ES276_08850) - 1636944..1637930 (-) 987 WP_000446975.1 glycosyltransferase family 2 protein -
  ES276_RS08330 (ES276_08855) - 1637932..1639035 (-) 1104 WP_000225889.1 glycosyltransferase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28363.15 Da        Isoelectric Point: 4.0199

>NTDB_id=352644 ES276_RS08310 WP_000782664.1 1633495..1634232(-) (mecA) [Streptococcus pneumoniae strain TVO_1901936]
MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMSHDAVLN
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=352644 ES276_RS08310 WP_000782664.1 1633495..1634232(-) (mecA) [Streptococcus pneumoniae strain TVO_1901936]
ATGAAAATGAAACAAATTAGTGATACAACTTTAAAAATCACGATATCTTTAGAGGATTTGATGGATCGTGGAATGGAGAT
TGCTGACTTTCTCGTTCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCTATCTTGGATGAGCTAGAGATGCCTGATAGCT
TTCTGGATACAGGCATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTAGATGTCTTTGTGACCAAGTCAAAGATT
GACCAAAATCTAGATTTTGAAGACTTATCGGATTTGCCAGATATGGAAGAATTGGCTCAAATGTCTCCAGATGAATTTAT
CAAAACCCTGGAAAAAAGCATCGCAGACAAAACCAAGGATGATATCGAAGCCATTCAATCTCTTGAGCAAGTTGAAGCCA
AGGAAGAAGAGCAAGAGCAGGCTGAACAAGAAGCTGAGAGTAAGAAAGAACCTTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTAGCTTTTGCCAAGACAGTGACTTTTGAAATGGAAACTTCTGAACTCTACAAAATGAACGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGCCCATATCCAGCTTGGCTGTTGGCCCGTATGCGCGAGT
TTGCAGACGATAGTGATATCAGTCGCTCAGTCTTACAAGAGTATGGTCAAGTCTTGATGAGTCACGATGCAGTGCTCAAT
CTGCAAAAAATCGGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

100

100

1
  mecA Streptococcus pneumoniae D39

100

100

1
  mecA Streptococcus pneumoniae R6

100

100

1
  mecA Streptococcus pneumoniae TIGR4

99.592

100

0.996
  mecA Streptococcus thermophilus LMD-9

48.193

100

0.49
  mecA Streptococcus thermophilus LMG 18311

47.791

100

0.486
  mecA Streptococcus mutans UA159

48.571

100

0.486

Multiple sequence alignment