Detailed information NTG0352575

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: ES300_RS09500
• Genome accession: NZ_CP038251
• Coordinates: 1859868..1860170 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413380.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901944
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1854868..1865170

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES300_RS09470 (ES300_09975)	rnpA	1855548..1855919 (-)	372	WP_000739246.1	ribonuclease P protein component	-
ES300_RS10695	-	1855936..1856067 (-)	132	WP_000768904.1	hypothetical protein	-
ES300_RS09475 (ES300_09980)	-	1856068..1857258 (-)	1191	WP_000167768.1	acetate kinase	-
ES300_RS09480 (ES300_09985)	comYH	1857309..1858262 (-)	954	WP_000345086.1	class I SAM-dependent methyltransferase	Machinery gene
ES300_RS09485 (ES300_09990)	-	1858323..1858917 (-)	595	Protein_1873	class I SAM-dependent methyltransferase	-
ES300_RS09490 (ES300_09995)	comGG/cglG	1859020..1859466 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
ES300_RS09495 (ES300_10000)	comGF/cglF	1859444..1859905 (-)	462	WP_000250523.1	competence type IV pilus minor pilin ComGF	Machinery gene
ES300_RS09500 (ES300_10005)	comGE/cglE	1859868..1860170 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
ES300_RS09505 (ES300_10010)	comGD/cglD	1860133..1860537 (-)	405	WP_000588023.1	competence type IV pilus minor pilin ComGD	Machinery gene
ES300_RS09510 (ES300_10015)	comGC/cglC	1860530..1860856 (-)	327	WP_000738621.1	comG operon protein ComGC	Machinery gene
ES300_RS09515 (ES300_10020)	comGB/cglB	1860858..1861874 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
ES300_RS09520 (ES300_10025)	comGA/cglA/cilD	1861822..1862763 (-)	942	WP_000249568.1	competence type IV pilus ATPase ComGA	Machinery gene
ES300_RS09525 (ES300_10030)	-	1862839..1863204 (-)	366	WP_238123406.1	DUF1033 family protein	-
ES300_RS09530 (ES300_10035)	-	1863355..1864413 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11135.11 Da
• Isoelectric Point: 9.7273

>NTDB_id=352575 ES300_RS09500 WP_000413380.1 1859868..1860170(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901944]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=352575 ES300_RS09500 WP_000413380.1 1859868..1860170(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901944]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus mitis NCTC 12261	99	100	0.99
comGE/cglE	Streptococcus pneumoniae Rx1	99	100	0.99
comGE/cglE	Streptococcus pneumoniae D39	99	100	0.99
comGE/cglE	Streptococcus pneumoniae R6	99	100	0.99
comGE/cglE	Streptococcus pneumoniae TIGR4	99	100	0.99
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	43.333	90	0.39
comYE	Streptococcus mutans UA159	43.333	90	0.39