Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   ES300_RS09480 Genome accession   NZ_CP038251
Coordinates   1857309..1858262 (-) Length   317 a.a.
NCBI ID   WP_000345086.1    Uniprot ID   A0A064C057
Organism   Streptococcus pneumoniae strain TVO_1901944     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1852309..1863262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES300_RS09455 (ES300_09960) - 1853070..1853693 (-) 624 WP_000932635.1 hypothetical protein -
  ES300_RS09460 (ES300_09965) jag 1853744..1854730 (-) 987 WP_000260009.1 RNA-binding cell elongation regulator Jag/EloR -
  ES300_RS09465 (ES300_09970) - 1854749..1855573 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  ES300_RS09470 (ES300_09975) rnpA 1855548..1855919 (-) 372 WP_000739246.1 ribonuclease P protein component -
  ES300_RS10695 - 1855936..1856067 (-) 132 WP_000768904.1 hypothetical protein -
  ES300_RS09475 (ES300_09980) - 1856068..1857258 (-) 1191 WP_000167768.1 acetate kinase -
  ES300_RS09480 (ES300_09985) comYH 1857309..1858262 (-) 954 WP_000345086.1 class I SAM-dependent methyltransferase Machinery gene
  ES300_RS09485 (ES300_09990) - 1858323..1858917 (-) 595 Protein_1873 class I SAM-dependent methyltransferase -
  ES300_RS09490 (ES300_09995) comGG/cglG 1859020..1859466 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  ES300_RS09495 (ES300_10000) comGF/cglF 1859444..1859905 (-) 462 WP_000250523.1 competence type IV pilus minor pilin ComGF Machinery gene
  ES300_RS09500 (ES300_10005) comGE/cglE 1859868..1860170 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  ES300_RS09505 (ES300_10010) comGD/cglD 1860133..1860537 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  ES300_RS09510 (ES300_10015) comGC/cglC 1860530..1860856 (-) 327 WP_000738621.1 comG operon protein ComGC Machinery gene
  ES300_RS09515 (ES300_10020) comGB/cglB 1860858..1861874 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  ES300_RS09520 (ES300_10025) comGA/cglA/cilD 1861822..1862763 (-) 942 WP_000249568.1 competence type IV pilus ATPase ComGA Machinery gene
  ES300_RS09525 (ES300_10030) - 1862839..1863204 (-) 366 WP_238123406.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35676.86 Da        Isoelectric Point: 4.2270

>NTDB_id=352572 ES300_RS09480 WP_000345086.1 1857309..1858262(-) (comYH) [Streptococcus pneumoniae strain TVO_1901944]
MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=352572 ES300_RS09480 WP_000345086.1 1857309..1858262(-) (comYH) [Streptococcus pneumoniae strain TVO_1901944]
ATGGATTTTGAAAAAATTGAACAAGCTTATATCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTATTTATTGTGGAAGAGTTGTTTAC
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGTCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGTTTAAGTACCTTAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C057

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment