Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   E3C75_RS03875 Genome accession   NZ_CP038020
Coordinates   729623..731140 (+) Length   505 a.a.
NCBI ID   WP_111679253.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ATCC 19258     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 724623..736140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3C75_RS11510 - 724903..725073 (+) 171 Protein_715 ascorbate 6-phosphate lactonase -
  E3C75_RS03850 - 725090..725761 (-) 672 WP_064355629.1 TrkA family potassium uptake protein -
  E3C75_RS03855 - 725801..727165 (-) 1365 WP_111679249.1 potassium transporter TrkG -
  E3C75_RS03860 rsmG 727235..727948 (-) 714 WP_002949634.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  E3C75_RS03865 - 728245..728781 (+) 537 WP_111679251.1 YceD family protein -
  E3C75_RS03870 covR 728937..729626 (+) 690 WP_084828484.1 response regulator transcription factor Regulator
  E3C75_RS03875 covS 729623..731140 (+) 1518 WP_111679253.1 HAMP domain-containing histidine kinase Regulator
  E3C75_RS03880 nrdR 731263..731742 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  E3C75_RS03885 - 731739..732914 (+) 1176 WP_111679255.1 DnaD domain protein -
  E3C75_RS03890 dnaI 732918..733820 (+) 903 WP_084828487.1 primosomal protein DnaI -
  E3C75_RS03895 der 733926..735236 (+) 1311 WP_084828488.1 ribosome biogenesis GTPase Der -
  E3C75_RS11255 - 735300..735968 (+) 669 Protein_726 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57569.02 Da        Isoelectric Point: 5.3841

>NTDB_id=351401 E3C75_RS03875 WP_111679253.1 729623..731140(+) (covS) [Streptococcus thermophilus strain ATCC 19258]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAAFY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLKFYYALKERLIFLLIFLEVGMTVLVIAVIVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQEDNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=351401 E3C75_RS03875 WP_111679253.1 729623..731140(+) (covS) [Streptococcus thermophilus strain ATCC 19258]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCTTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGAAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAATTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACAATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAGATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGTCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

ArlS sensor domain (ArlS_N)

(39-187)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.024

99.406

0.935

Multiple sequence alignment