Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvB   Type   Machinery gene
Locus tag   GL188_RS01290 Genome accession   NZ_CP046359
Coordinates   233066..234064 (+) Length   332 a.a.
NCBI ID   WP_001860761.1    Uniprot ID   C1CC50
Organism   Streptococcus pneumoniae strain 573     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 228066..239064
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL188_RS01270 (GL188_01335) leuS 228207..230708 (+) 2502 WP_000011766.1 leucine--tRNA ligase -
  GL188_RS01275 (GL188_01340) - 230902..231597 (+) 696 WP_001144922.1 GNAT family N-acetyltransferase -
  GL188_RS01280 (GL188_01345) - 231609..232025 (+) 417 WP_000628392.1 GNAT family N-acetyltransferase -
  GL188_RS01285 (GL188_01350) - 232840..232932 (-) 93 WP_000970381.1 type I toxin-antitoxin system Fst family toxin -
  GL188_RS01290 (GL188_01355) ruvB 233066..234064 (+) 999 WP_001860761.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  GL188_RS01295 (GL188_01360) - 234045..234617 (+) 573 WP_001098895.1 nucleotidyltransferase family protein -
  GL188_RS01300 (GL188_01365) - 234848..235606 (+) 759 WP_000466714.1 isoprenyl transferase -
  GL188_RS01305 (GL188_01370) - 235615..236418 (+) 804 WP_000189848.1 phosphatidate cytidylyltransferase -
  GL188_RS01310 (GL188_01375) eeP 236440..237699 (+) 1260 WP_000900659.1 RIP metalloprotease RseP Regulator

Sequence

Protein


Download         Length: 332 a.a.        Molecular weight: 37230.69 Da        Isoelectric Point: 4.5393

>NTDB_id=351196 GL188_RS01290 WP_001860761.1 233066..234064(+) (ruvB) [Streptococcus pneumoniae strain 573]
MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPVIEKAGDLVAILNELEPGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYAHAGLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRVRDFAQIMGNGVID
DIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAK
AYEHLGYEYSEK

Nucleotide


Download         Length: 999 bp        

>NTDB_id=351196 GL188_RS01290 WP_001860761.1 233066..234064(+) (ruvB) [Streptococcus pneumoniae strain 573]
ATGAGTAGAATTTTAGATAATGAGATAATGGGGGATGAGGAGTTAGTAGAACGCACGCTCCGTCCTCAGTATTTACGTGA
ATATATCGGACAGGATAAGGTCAAGGACCAGCTACAAATCTTTATTGAAGCTGCCAAAATGCGGGATGAAGCGCTGGATC
ATGTGCTCTTATTTGGGCCTCCAGGTCTCGGGAAAACGACCATGGCCTTTGTTATTGCCAACGAACTGGGAGTCAATCTT
AAGCAGACGTCGGGTCCAGTCATTGAAAAAGCCGGAGATCTGGTAGCTATTTTGAATGAGTTAGAGCCTGGGGATGTACT
TTTTATTGATGAGATCCATCGTTTGCCAATGTCAGTGGAAGAGGTGCTTTATAGTGCTATGGAGGACTTCTACATCGATA
TTATGATTGGGGCTGGTGAGGGTAGTCGTAGTGTTCATTTGGAGTTACCACCTTTTACCTTGATTGGTGCGACGACTCGG
GCTGGTATGCTCTCCAATCCGCTACGGGCACGTTTTGGGATTACAGGCCATATGGAGTATTATGCCCATGCTGGCTTGAC
AGAAATTGTCGAGCGGACGGCAGATATTTTTGAGATGGAAATCACTCATGAGGCAGCATCTGAGTTGGCCCTACGTAGTC
GTGGGACCCCTCGTATTGCCAATCGTCTCCTCAAGCGCGTGCGCGATTTTGCCCAGATAATGGGGAATGGGGTAATTGAT
GATATTATTACCGATAAGGCTTTGACTATGCTGGATGTTGACCATGAAGGTTTGGACTATGTGGATCAAAAAATCCTTCG
TACCATGATTGAGATGTACAGTGGAGGACCTGTTGGTCTAGGAACTCTTTCTGTGAATATCGCCGAAGAGCGTGAGACAG
TTGAAGATATGTATGAGCCTTACTTGATTCAAAAAGGTTTTATCATGCGGACACGGTCTGGACGGGTGGCGACTGCTAAG
GCATATGAGCACTTAGGTTATGAATACAGTGAAAAATAA

Domains

Predicted by InterProScan.

RuvB C-terminal winged helix domain (WHD_RuvB)

(256-325)

RuvB AAA lid domain (AAA_lid_4)

(181-254)

Holliday junction DNA helicase RuvB P-loop domain (RuvB_N)

(20-178)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CC50

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvB Streptococcus pneumoniae R6

99.699

100

0.997
  ruvB Streptococcus pneumoniae D39

99.699

100

0.997
  ruvB Streptococcus pneumoniae TIGR4

98.795

100

0.988
  ruvB Bacillus subtilis subsp. subtilis str. 168

60.429

98.193

0.593
  ruvB Helicobacter pylori 26695

50.774

97.289

0.494
  ruvB Synechocystis sp. PCC 6803

48.193

100

0.482

Multiple sequence alignment