Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   MGAS15252_RS07955 Genome accession   NC_017040
Coordinates   1657361..1657957 (-) Length   198 a.a.
NCBI ID   WP_002992186.1    Uniprot ID   P0DF49
Organism   Streptococcus pyogenes MGAS15252     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1652361..1662957
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS15252_RS07920 (MGAS15252_1640) - 1652420..1652725 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  MGAS15252_RS07925 (MGAS15252_1641) ruvX 1652737..1653156 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  MGAS15252_RS07930 (MGAS15252_1642) - 1653153..1653422 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  MGAS15252_RS07935 (MGAS15252_1643) spx 1653537..1653935 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  MGAS15252_RS07940 (MGAS15252_1644) recA 1654226..1655362 (-) 1137 WP_014407932.1 recombinase RecA -
  MGAS15252_RS07945 (MGAS15252_1645) cinA 1655451..1656722 (-) 1272 WP_014407933.1 competence/damage-inducible protein A Machinery gene
  MGAS15252_RS07950 (MGAS15252_1646) - 1656791..1657351 (-) 561 WP_010922755.1 DNA-3-methyladenine glycosylase I -
  MGAS15252_RS07955 (MGAS15252_1647) ruvA 1657361..1657957 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  MGAS15252_RS07960 (MGAS15252_1648) - 1657959..1659179 (-) 1221 WP_014407934.1 MDR family MFS transporter -
  MGAS15252_RS07965 (MGAS15252_1649) hexB 1659190..1661172 (-) 1983 WP_014407935.1 DNA mismatch repair endonuclease MutL Machinery gene
  MGAS15252_RS07970 (MGAS15252_1650) - 1661267..1662418 (-) 1152 WP_014407936.1 tyrosine-type recombinase/integrase -
  MGAS15252_RS09255 (MGAS15252_1651) - 1662740..1662883 (+) 144 WP_011185066.1 putative holin-like toxin -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21879.26 Da        Isoelectric Point: 6.8838

>NTDB_id=35091 MGAS15252_RS07955 WP_002992186.1 1657361..1657957(-) (ruvA) [Streptococcus pyogenes MGAS15252]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=35091 MGAS15252_RS07955 WP_002992186.1 1657361..1657957(-) (ruvA) [Streptococcus pyogenes MGAS15252]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGGTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCTCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.887

100

0.419

Multiple sequence alignment