Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   GKC13_RS01710 Genome accession   NZ_CP046134
Coordinates   319560..320927 (+) Length   455 a.a.
NCBI ID   WP_084829837.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MAG_rmk202_sterm     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 314560..325927
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GKC13_RS01700 (GKC13_01690) - 314632..316377 (+) 1746 WP_207559840.1 ABC transporter ATP-binding protein -
  GKC13_RS01705 (GKC13_01695) comA/nlmT 317391..319544 (+) 2154 WP_207559839.1 peptide cleavage/export ABC transporter Regulator
  GKC13_RS01710 (GKC13_01700) comB 319560..320927 (+) 1368 WP_084829837.1 bacteriocin secretion accessory protein Regulator
  GKC13_RS01715 (GKC13_01705) - 320942..321103 (+) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  GKC13_RS09850 - 321121..321924 (-) 804 WP_240892566.1 ATP-binding protein -
  GKC13_RS01725 (GKC13_01715) comE/blpR 322461..323192 (-) 732 WP_207559838.1 response regulator transcription factor Regulator
  GKC13_RS01730 (GKC13_01720) - 323448..323624 (+) 177 WP_011681570.1 Blp family class II bacteriocin -
  GKC13_RS01735 (GKC13_01725) - 323643..323843 (+) 201 WP_011681569.1 hypothetical protein -
  GKC13_RS01740 (GKC13_01730) - 324199..324429 (+) 231 WP_014608662.1 bacteriocin class II family protein -
  GKC13_RS10455 (GKC13_01740) - 325434..325835 (+) 402 WP_024703992.1 hypothetical protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50399.10 Da        Isoelectric Point: 4.7492

>NTDB_id=350145 GKC13_RS01710 WP_084829837.1 319560..320927(+) (comB) [Streptococcus thermophilus strain MAG_rmk202_sterm]
MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEVTVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKV
VKKGDTLVQYSETMEASQKEGLQKQLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKT
NTEVNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVN
TNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQITDTESKINQADVLLTNTLIQSPED
GILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSAT
ETERGNVFRVTARASISEKEAQNLRYGLESRVTSVIDQKTYFNYFKDKLLNLQDQ

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=350145 GKC13_RS01710 WP_084829837.1 319560..320927(+) (comB) [Streptococcus thermophilus strain MAG_rmk202_sterm]
ATGAATCCACAGTTGTTTAAAAGCACAGAGTTTTACCATCGTCGCTACCACAATATGTCTACTGTTTTGATTACTCCCTT
GATTTTGTTAGTTATTTTCCTTTTTCTTTTCGCTTTTTTTGCTAAGAAGGAAGTTACAGTCACGTCTAGAGGAAGTATAG
AGCCAACCAAGGTTATCGCAGTAATCCAATCAACCAGTGACAATACCATCATAGATAATCAACTGGTTGCTAATAAGGTT
GTTAAAAAAGGGGACACCTTAGTTCAGTATTCAGAGACCATGGAGGCATCGCAAAAAGAGGGGCTTCAAAAGCAACTAGA
ACTTTTAAAAAGACAGGAATCAGGTTTGAAGACCTTGCAATCTAGCCTAACGCAGGGAACCAATCTTTTCCAAGAACAGG
AAGACGAGTTTGGTTATCAGAGTACTTTTAACACCTACCTAAGTCAGGCACAGGATATTGACTTGGGTGTGGCTAAAACA
AATACAGAGGTTAATAACCAAGCAGCAATTGCGAGTAATACCGGTTCTGCTATTGATAACCAGATTAGTCAATTGCAGAC
TCAGGTCTCAGAGTATGAGGCGCTCTCTCAAGCTATTACCAATCATGAAACGACTTTACCTGAAGGCAATCCTCATCAGG
CAACCTTAAATGCCTATAACAGTCAGTATGCTACGACACCGGATGCCAGTGTAACAGACCAATACCTATCTCAAGTTAAT
ACCAATATTTCGAGCTTGAATGCTTCCATAGGTAATCTAGAAATCCAAAAGGCTGGGACAGGCACAGTTGTAACTTATGA
CAATAGTGATAGCACTAAAAAAGAAGCTCTAAAAAATCAATTCTTGCAAAATGCAGGACAGCAATTGAGCTCAGTGGAAA
CACAAATTACCGATACCGAGAGTAAAATCAATCAGGCAGATGTCCTTCTGACTAATACCCTCATCCAGTCACCAGAAGAT
GGAATCTTACACTTGAGTCAAGCTGATAAAAAAGCAACCATGGCTGCGACAGGAACTGAGTTGGCCCAGCTTTATCCCGA
TATGACTCAAACCCAGGAAGTTGCCATTACTTATTATGTGAATTCGGATTATGTGCCAAAACTGCAAAAAGGCCAGTCAG
TTCGACTGACCTTGGATAAGGTTGGTAATCACGGTACCACAATTATTGGAAAACTTGAGAGTATTGATAATTCTGCCACG
GAAACAGAAAGGGGGAATGTGTTTAGAGTAACTGCTAGGGCAAGTATTTCAGAAAAAGAAGCCCAAAATCTACGTTACGG
TCTAGAAAGTCGTGTGACAAGCGTTATTGACCAAAAGACCTACTTCAATTACTTTAAAGACAAGTTACTAAACTTGCAAG
ACCAATAG

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(315-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

39.246

99.121

0.389
  comB Streptococcus pneumoniae D39

39.246

99.121

0.389
  comB Streptococcus pneumoniae R6

39.246

99.121

0.389
  comB Streptococcus pneumoniae TIGR4

38.581

99.121

0.382
  comB Streptococcus mitis SK321

37.916

99.121

0.376
  comB Streptococcus mitis NCTC 12261

37.916

99.121

0.376