Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   GKC13_RS01725 Genome accession   NZ_CP046134
Coordinates   322461..323192 (-) Length   243 a.a.
NCBI ID   WP_207559838.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MAG_rmk202_sterm     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 317461..328192
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GKC13_RS01710 (GKC13_01700) comB 319560..320927 (+) 1368 WP_084829837.1 bacteriocin secretion accessory protein Regulator
  GKC13_RS01715 (GKC13_01705) - 320942..321103 (+) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  GKC13_RS09850 - 321121..321924 (-) 804 WP_240892566.1 ATP-binding protein -
  GKC13_RS01725 (GKC13_01715) comE/blpR 322461..323192 (-) 732 WP_207559838.1 response regulator transcription factor Regulator
  GKC13_RS01730 (GKC13_01720) - 323448..323624 (+) 177 WP_011681570.1 Blp family class II bacteriocin -
  GKC13_RS01735 (GKC13_01725) - 323643..323843 (+) 201 WP_011681569.1 hypothetical protein -
  GKC13_RS01740 (GKC13_01730) - 324199..324429 (+) 231 WP_014608662.1 bacteriocin class II family protein -
  GKC13_RS10455 (GKC13_01740) - 325434..325835 (+) 402 WP_024703992.1 hypothetical protein -
  GKC13_RS01745 (GKC13_01745) - 326086..326340 (+) 255 WP_014608660.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27731.04 Da        Isoelectric Point: 7.1717

>NTDB_id=350146 GKC13_RS01725 WP_207559838.1 322461..323192(-) (comE/blpR) [Streptococcus thermophilus strain MAG_rmk202_sterm]
MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGGTIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=350146 GKC13_RS01725 WP_207559838.1 322461..323192(-) (comE/blpR) [Streptococcus thermophilus strain MAG_rmk202_sterm]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGAGGCTGTGGCACATGAACTTAAATCCTT
CGGAAAAGATCTATCTTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATCGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGGAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGATATGATCATCTCTGTCAACAAGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTTCTACCAGTATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-119)

LytTr DNA-binding domain (LytTR)

(146-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.628

100

0.362