Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilE   Type   Machinery gene
Locus tag   NMO_RS11015 Genome accession   NC_013016
Coordinates   2142220..2142723 (+) Length   167 a.a.
NCBI ID   WP_015815999.1    Uniprot ID   C6S9P1
Organism   Neisseria meningitidis alpha14     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2137220..2147723
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMO_RS14910 - 2137569..2137778 (+) 210 Protein_2055 pilin -
  NMO_RS14915 - 2137797..2138132 (+) 336 Protein_2056 pilin -
  NMO_RS14990 - 2138609..2138734 (+) 126 Protein_2057 pilin -
  NMO_RS10995 (NMO_1982) - 2138882..2139889 (-) 1008 WP_048816174.1 IS5 family transposase -
  NMO_RS14820 - 2139962..2140219 (+) 258 Protein_2059 pilin -
  NMO_RS11005 (NMO_1984) - 2140260..2140655 (+) 396 Protein_2060 pilin -
  NMO_RS11010 (NMO_1985) - 2141062..2141447 (+) 386 Protein_2061 pilin -
  NMO_RS11015 (NMO_1986) pilE 2142220..2142723 (+) 504 WP_015815999.1 pilin Machinery gene
  NMO_RS11020 (NMO_1987) lpxC 2143753..2144676 (+) 924 WP_002216134.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -

Sequence

Protein


Download         Length: 167 a.a.        Molecular weight: 17696.05 Da        Isoelectric Point: 7.1329

>NTDB_id=34992 NMO_RS11015 WP_015815999.1 2142220..2142723(+) (pilE) [Neisseria meningitidis alpha14]
MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQKSAVTEYYLNHGEWPSDNSAAGVASSSTIK
GKYVKEVTVANGVVTAEMKSSGVNKEIKDKKLSLWAKRQDGSVKWFCGQPVTRTAADSDDVAAATDANGKIDTKHLPSTC
RDASSAS

Nucleotide


Download         Length: 504 bp        

>NTDB_id=34992 NMO_RS11015 WP_015815999.1 2142220..2142723(+) (pilE) [Neisseria meningitidis alpha14]
ATGAACACCCTTCAAAAAGGTTTTACCCTTATCGAGCTGATGATTGTGATTGCCATCGTCGGCATTTTGGCGGCAGTCGC
CCTTCCTGCTTATCAAGACTACACAGCCCGCGCACAAGTTTCCGAAGCCATTCTTTTGGCTGAAGGTCAAAAATCAGCCG
TCACCGAGTATTACCTGAATCACGGCGAATGGCCATCCGACAATAGTGCCGCCGGCGTGGCATCTTCTTCAACAATCAAA
GGAAAATATGTTAAGGAAGTTACAGTCGCAAACGGCGTCGTTACCGCAGAAATGAAATCAAGCGGCGTAAACAAAGAAAT
CAAAGACAAAAAACTCTCCCTGTGGGCCAAGCGTCAAGACGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTACGCGCA
CCGCCGCCGACAGCGACGACGTCGCCGCCGCCACCGACGCCAACGGCAAGATCGACACCAAGCACCTGCCGTCAACCTGC
CGCGACGCTTCATCTGCCAGCTAA

Domains

Predicted by InterproScan.

Pilin (bacterial filament) (Pilin)

(36-161)

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C6S9P1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilE Neisseria gonorrhoeae strain FA1090

85.629

100

0.856
  pilE Neisseria gonorrhoeae MS11

81.928

99.401

0.814
  pilE Neisseria elongata subsp. glycolytica ATCC 29315

35.079

100

0.401
  comP Acinetobacter baylyi ADP1

38.095

100

0.383
  pilA/pilA1 Eikenella corrodens VA1

37.725

100

0.377

Multiple sequence alignment