Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   HELPY_RS00230 Genome accession   NC_012973
Coordinates   39170..40300 (+) Length   376 a.a.
NCBI ID   WP_001045895.1    Uniprot ID   -
Organism   Helicobacter pylori B38     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 34170..45300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HELPY_RS00195 (HELPY_0032) panD 34594..34947 (+) 354 WP_000142262.1 aspartate 1-decarboxylase -
  HELPY_RS00200 (HELPY_0033) - 34950..35252 (+) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  HELPY_RS00205 (HELPY_0034) - 35252..36256 (+) 1005 WP_000468457.1 PDZ domain-containing protein -
  HELPY_RS00210 (HELPY_0035) comB6 36264..37319 (+) 1056 WP_000786644.1 P-type conjugative transfer protein TrbL Machinery gene
  HELPY_RS00215 comB7 37335..37448 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  HELPY_RS00220 (HELPY_0036) comB8 37445..38188 (+) 744 WP_001208405.1 type IV secretion system protein Machinery gene
  HELPY_RS00225 (HELPY_0037) comB9 38188..39177 (+) 990 WP_012777816.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HELPY_RS00230 (HELPY_0038) comB10 39170..40300 (+) 1131 WP_001045895.1 DNA type IV secretion system protein ComB10 Machinery gene
  HELPY_RS00235 (HELPY_0039) - 40371..41783 (+) 1413 WP_000694863.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HELPY_RS00240 (HELPY_0040) gmd 41824..42969 (+) 1146 WP_000659814.1 GDP-mannose 4,6-dehydratase -
  HELPY_RS00245 (HELPY_0041) - 42962..43894 (+) 933 WP_001002506.1 GDP-L-fucose synthase family protein -
  HELPY_RS00250 (HELPY_0042) hypE 44210..45208 (-) 999 WP_000378793.1 hydrogenase expression/formation protein HypE -

Sequence

Protein


Download         Length: 376 a.a.        Molecular weight: 41956.56 Da        Isoelectric Point: 9.9021

>NTDB_id=34838 HELPY_RS00230 WP_001045895.1 39170..40300(+) (comB10) [Helicobacter pylori B38]
MNKWLKGVLIFIGGFATIVTISLVYHQKPKAPLNNQPSLLNDDEVKYPLQDYTFTQNPQPTNTESSKDATIKALQEQLKA
ALKALNSKEMNYSKEETFKSPPIDPKTTPPKKDFSLKQLDLLAARITPFKQSPKNYEENLIFPVDNPNGIDGFTNLKEKD
IATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFAHMGKAVLIPKGSKVIGYYSNNNKMGEYRLDIVWSRI
ITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGVPLLLSTLTNGLLIGITSALNNRGNKEGATNFFGDYLLMQLMR
QSGMGINQVVNQILRDKSKIAPIVVIREGSRVFISPNTDIFFPIPRENEVIAEFLK

Nucleotide


Download         Length: 1131 bp        

>NTDB_id=34838 HELPY_RS00230 WP_001045895.1 39170..40300(+) (comB10) [Helicobacter pylori B38]
ATGAATAAGTGGCTTAAGGGGGTGCTTATTTTTATAGGGGGTTTTGCAACGATTGTAACCATTTCTTTAGTCTATCATCA
AAAGCCAAAAGCCCCCTTAAATAACCAGCCTAGCCTTTTAAATGACGATGAGGTGAAATACCCCTTACAAGACTACACCT
TCACTCAAAACCCACAGCCAACTAACACAGAAAGCTCCAAAGACGCTACCATCAAAGCCTTACAAGAACAGCTCAAAGCC
GCTTTAAAAGCCCTAAACTCCAAAGAAATGAATTATTCCAAAGAAGAAACTTTTAAGAGCCCTCCCATAGATCCAAAAAC
AACCCCCCCTAAAAAAGACTTTTCTCTAAAGCAATTAGATTTATTAGCCGCTCGCATCACCCCCTTCAAACAAAGCCCTA
AAAATTACGAAGAAAACTTGATTTTCCCTGTGGATAACCCTAATGGCATTGATGGTTTCACTAACCTTAAAGAAAAAGAC
ATTGCCACTAATGAAAACAAGCTTTTACGCACCATTACGGCTGACAAAATGATACCCGCCTTTTTGATCACGCCCATTTC
TAGCCAGATCGCTGGTAAAGTGATTGCGCAAGTGGAGAGCGATATTTTTGCTCACATGGGCAAGGCCGTCTTAATCCCCA
AAGGCTCTAAAGTCATAGGCTATTACAGCAACAATAACAAAATGGGCGAATACCGCTTGGATATTGTATGGAGCCGCATC
ATCACTCCCCATGGGATTAATATCATGCTCACTAACGCTAAGGGGGCGGACATTAAAGGTTATAACGGCTTAGTGGGGGA
ATTGATTGAAAGGAATTTCCAGCGCTATGGCGTGCCGTTACTGCTTTCTACGCTCACTAACGGCCTATTGATTGGGATCA
CTTCGGCTTTAAACAACAGAGGCAATAAAGAAGGAGCCACCAATTTCTTTGGGGATTATCTTTTAATGCAATTGATGAGA
CAAAGCGGCATGGGGATCAATCAAGTGGTCAATCAAATTTTAAGAGACAAGAGCAAGATCGCTCCCATTGTGGTGATTAG
AGAGGGAAGTAGGGTTTTCATTTCGCCCAATACTGACATCTTTTTCCCTATACCCAGAGAAAATGAAGTCATCGCTGAGT
TTTTGAAGTGA

Domains

Predicted by InterproScan.

Bacterial conjugation TrbI-like protein (TrbI)

(171-362)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

98.67

100

0.987

Multiple sequence alignment