Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HELPY_RS00220 Genome accession   NC_012973
Coordinates   37445..38188 (+) Length   247 a.a.
NCBI ID   WP_001208405.1    Uniprot ID   -
Organism   Helicobacter pylori B38     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32445..43188
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HELPY_RS00195 (HELPY_0032) panD 34594..34947 (+) 354 WP_000142262.1 aspartate 1-decarboxylase -
  HELPY_RS00200 (HELPY_0033) - 34950..35252 (+) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  HELPY_RS00205 (HELPY_0034) - 35252..36256 (+) 1005 WP_000468457.1 PDZ domain-containing protein -
  HELPY_RS00210 (HELPY_0035) comB6 36264..37319 (+) 1056 WP_000786644.1 P-type conjugative transfer protein TrbL Machinery gene
  HELPY_RS00215 comB7 37335..37448 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  HELPY_RS00220 (HELPY_0036) comB8 37445..38188 (+) 744 WP_001208405.1 type IV secretion system protein Machinery gene
  HELPY_RS00225 (HELPY_0037) comB9 38188..39177 (+) 990 WP_012777816.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HELPY_RS00230 (HELPY_0038) comB10 39170..40300 (+) 1131 WP_001045895.1 DNA type IV secretion system protein ComB10 Machinery gene
  HELPY_RS00235 (HELPY_0039) - 40371..41783 (+) 1413 WP_000694863.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HELPY_RS00240 (HELPY_0040) gmd 41824..42969 (+) 1146 WP_000659814.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28695.92 Da        Isoelectric Point: 8.9604

>NTDB_id=34836 HELPY_RS00220 WP_001208405.1 37445..38188(+) (comB8) [Helicobacter pylori B38]
MREKPFNSEQLIYLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=34836 HELPY_RS00220 WP_001208405.1 37445..38188(+) (comB8) [Helicobacter pylori B38]
ATGAGAGAAAAGCCTTTCAACAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTAAGTGATTTGGACATGCAAAGCGTGTTCAGACTGGAGAGGAACCGCTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTATTTTAGCGATCGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAACATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCCATTGCCGCTAAACTTTTGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTATTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGTTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

99.19

100

0.992

Multiple sequence alignment