Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EXA24_RS00925 Genome accession   NZ_CP036376
Coordinates   145100..145855 (+) Length   251 a.a.
NCBI ID   WP_000425370.1    Uniprot ID   A0AAV3JI59
Organism   Streptococcus agalactiae strain Sag153     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 140100..150855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA24_RS00910 (EXA24_00915) - 140517..142067 (-) 1551 WP_000722386.1 ABC transporter substrate-binding protein/permease -
  EXA24_RS00915 (EXA24_00920) - 142203..144095 (+) 1893 WP_000710502.1 DUF2207 domain-containing protein -
  EXA24_RS00920 (EXA24_00925) - 144141..144980 (+) 840 WP_000905325.1 undecaprenyl-diphosphate phosphatase -
  EXA24_RS00925 (EXA24_00930) mecA 145100..145855 (+) 756 WP_000425370.1 adaptor protein MecA Regulator
  EXA24_RS00930 (EXA24_00935) - 145857..147017 (+) 1161 WP_000612109.1 MraY family glycosyltransferase -
  EXA24_RS00935 (EXA24_00940) sufC 147182..147952 (+) 771 WP_000114502.1 Fe-S cluster assembly ATPase SufC -
  EXA24_RS00940 (EXA24_00945) sufD 147989..149251 (+) 1263 WP_000031278.1 Fe-S cluster assembly protein SufD -
  EXA24_RS00945 (EXA24_00950) - 149253..150485 (+) 1233 WP_000173347.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29028.87 Da        Isoelectric Point: 4.2155

>NTDB_id=348263 EXA24_RS00925 WP_000425370.1 145100..145855(+) (mecA) [Streptococcus agalactiae strain Sag153]
MEMKQISETTLKITISMEDLEDRGMELKDFLIPQEKTEEFFYSVMDELDLPENFKNSGMLSFRVTPKKDRIDVFVTKSEL
SKDLNLEELADLGDISKMSPEDFFKTLEQSMLEKGDTDAHAKLAEIENMMDKATQEVVEENVSEEQAEKEVETIGYVHYV
FDFDNIEAVVRFSQTIDFPIEASELYKNGKGYHMTILLDLENQPSYFANLMYARMLEHANVGTKTRAYLKEHSIQLIHDD
AISKLQMIEMG

Nucleotide


Download         Length: 756 bp        

>NTDB_id=348263 EXA24_RS00925 WP_000425370.1 145100..145855(+) (mecA) [Streptococcus agalactiae strain Sag153]
ATGGAAATGAAACAAATCAGTGAAACAACACTGAAAATTACAATTAGTATGGAAGATTTAGAAGATCGTGGTATGGAGCT
GAAAGATTTCCTAATCCCTCAGGAGAAGACTGAGGAATTTTTCTATTCTGTCATGGATGAATTAGACTTGCCAGAAAACT
TTAAAAATAGTGGTATGTTAAGTTTTCGAGTAACACCTAAAAAAGATCGCATTGATGTTTTTGTTACAAAGTCTGAATTA
AGTAAAGATTTAAATTTAGAAGAATTAGCAGATTTGGGTGACATTTCAAAAATGTCTCCAGAAGACTTTTTTAAAACATT
GGAACAATCGATGTTGGAAAAAGGGGATACGGATGCCCATGCCAAATTAGCAGAAATTGAAAATATGATGGATAAAGCAA
CTCAAGAAGTAGTTGAGGAAAATGTTTCTGAAGAACAAGCTGAAAAGGAAGTAGAAACGATTGGATATGTTCACTATGTC
TTTGATTTTGATAATATTGAAGCTGTAGTTCGATTTTCACAAACGATTGATTTTCCAATAGAAGCTTCTGAACTCTATAA
AAATGGTAAAGGCTATCATATGACAATTTTGCTAGACTTGGAAAACCAACCAAGCTACTTTGCTAATTTGATGTATGCTC
GAATGCTTGAACATGCTAATGTGGGCACAAAAACACGAGCTTACTTGAAAGAGCATAGTATTCAATTGATTCATGATGAT
GCTATTTCAAAATTACAAATGATTGAGATGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

68.145

98.805

0.673
  mecA Streptococcus thermophilus LMD-9

59.438

99.203

0.59
  mecA Streptococcus thermophilus LMG 18311

58.635

99.203

0.582
  mecA Streptococcus pneumoniae Rx1

46.614

100

0.466
  mecA Streptococcus pneumoniae D39

46.614

100

0.466
  mecA Streptococcus pneumoniae R6

46.614

100

0.466
  mecA Streptococcus pneumoniae TIGR4

46.614

100

0.466

Multiple sequence alignment