Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   GII76_RS21230 Genome accession   NZ_CP045826
Coordinates   4099749..4100951 (-) Length   400 a.a.
NCBI ID   WP_015250812.1    Uniprot ID   A0ABU0V6N7
Organism   Bacillus subtilis strain 73     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4094749..4105951
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GII76_RS21205 (GII76_21205) - 4095699..4097150 (-) 1452 WP_069323037.1 HAMP domain-containing sensor histidine kinase -
  GII76_RS21210 (GII76_21210) - 4097147..4097830 (-) 684 WP_038428106.1 response regulator transcription factor -
  GII76_RS21215 (GII76_21215) - 4098042..4098941 (+) 900 WP_038428108.1 PepSY domain-containing protein -
  GII76_RS21220 (GII76_21220) - 4099102..4099602 (+) 501 WP_015250813.1 PepSY domain-containing protein -
  GII76_RS21225 (GII76_21225) - 4099599..4099728 (-) 130 Protein_4156 hypothetical protein -
  GII76_RS21230 (GII76_21230) htrA 4099749..4100951 (-) 1203 WP_015250812.1 serine protease HtrC Regulator
  GII76_RS21235 (GII76_21235) vicX 4101033..4101827 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  GII76_RS21240 (GII76_21240) walI 4101849..4102691 (-) 843 WP_029318542.1 WalRK two-component regulatory system regulator WalI -
  GII76_RS21245 (GII76_21245) walH 4102678..4104045 (-) 1368 WP_046664054.1 WalRK two-component regulatory system regulator WalH -
  GII76_RS21250 (GII76_21250) walK 4104035..4105870 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.5340

>NTDB_id=348100 GII76_RS21230 WP_015250812.1 4099749..4100951(-) (htrA) [Bacillus subtilis strain 73]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=348100 GII76_RS21230 WP_015250812.1 4099749..4100951(-) (htrA) [Bacillus subtilis strain 73]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTAGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGTAATGTGTCGCCCGCCGTTGTGGGTGTTGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAATTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(196-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378