Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   GII81_RS21810 Genome accession   NZ_CP045820
Coordinates   4197157..4198359 (-) Length   400 a.a.
NCBI ID   WP_015250812.1    Uniprot ID   A0ABU0V6N7
Organism   Bacillus subtilis strain MB9_B1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4192157..4203359
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GII81_RS21785 (GII81_21785) - 4193091..4194557 (-) 1467 WP_029726117.1 HAMP domain-containing sensor histidine kinase -
  GII81_RS21790 (GII81_21790) - 4194554..4195237 (-) 684 WP_024573086.1 response regulator transcription factor -
  GII81_RS21795 (GII81_21795) - 4195449..4196348 (+) 900 WP_029726116.1 PepSY domain-containing protein -
  GII81_RS21800 (GII81_21800) - 4196509..4197009 (+) 501 WP_029726115.1 PepSY domain-containing protein -
  GII81_RS21805 (GII81_21805) - 4197006..4197136 (-) 131 Protein_4275 hypothetical protein -
  GII81_RS21810 (GII81_21810) htrA 4197157..4198359 (-) 1203 WP_015250812.1 serine protease HtrC Regulator
  GII81_RS21815 (GII81_21815) vicX 4198441..4199235 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  GII81_RS21820 (GII81_21820) walI 4199257..4200099 (-) 843 WP_029726114.1 WalRK two-component regulatory system regulator WalI -
  GII81_RS21825 (GII81_21825) walH 4200086..4201453 (-) 1368 WP_029726113.1 WalRK two-component regulatory system regulator WalH -
  GII81_RS21830 (GII81_21830) walK 4201443..4203278 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.5340

>NTDB_id=347332 GII81_RS21810 WP_015250812.1 4197157..4198359(-) (htrA) [Bacillus subtilis strain MB9_B1]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=347332 GII81_RS21810 WP_015250812.1 4197157..4198359(-) (htrA) [Bacillus subtilis strain MB9_B1]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCAAG
CCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTAGATACGGGCG
CTTTAGATCAGCAGCAGAACAATAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATCGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGACTGAAGGAACTCGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTTGACATCAAGCTGTCGTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(196-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378