Detailed information NTG0034689

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SSUBM407_RS10455
• Genome accession: NC_012926
• Coordinates: 2144004..2145200 (+)
• Length: 398 a.a.
• NCBI ID: WP_012775711.1
• Uniprot ID: A0A0H3MYR1
• Organism: Streptococcus suis BM407
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2139004..2150200

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUBM407_RS10425 (SSUBM407_2029)	-	2139663..2142242 (+)	2580	WP_012028056.1	YfhO family protein	-
SSUBM407_RS10445 (SSUBM407_2030)	-	2142643..2143326 (-)	684	WP_012775416.1	YoaK family protein	-
SSUBM407_RS10450 (SSUBM407_2031)	rlmH	2143351..2143830 (-)	480	WP_012028058.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SSUBM407_RS10455 (SSUBM407_2032)	htrA	2144004..2145200 (+)	1197	WP_012775711.1	S1C family serine protease	Regulator
SSUBM407_RS10460 (SSUBM407_2033)	spo0J	2145261..2146025 (+)	765	WP_012775418.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41910.93 Da
• Isoelectric Point: 4.5940

>NTDB_id=34689 SSUBM407_RS10455 WP_012775711.1 2144004..2145200(+) (htrA) [Streptococcus suis BM407]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGVIFGNIESSDELAVAGEGSGVIYKKYGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSDLYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=34689 SSUBM407_RS10455 WP_012775711.1 2144004..2145200(+) (htrA) [Streptococcus suis BM407]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTGTCAGCCTCTTTCTTCCAGCCACAGGTGCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAATCAGCC
AACAATAGTCTTGGTGTTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAATATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCCGATACATATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGATCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

• PDZ domain (PDZ_2) (293-389)

3D structure

• AlphaFold DB: A0A0H3MYR1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.194	99.749	0.59
htrA	Streptococcus gordonii str. Challis substr. CH1	58.734	99.246	0.583
htrA	Streptococcus pneumoniae D39	56.997	98.744	0.563
htrA	Streptococcus pneumoniae TIGR4	56.997	98.744	0.563
htrA	Streptococcus mitis NCTC 12261	56.997	98.744	0.563
htrA	Streptococcus pneumoniae R6	56.997	98.744	0.563
htrA	Streptococcus pneumoniae Rx1	56.997	98.744	0.563