Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   GII85_RS20520 Genome accession   NZ_CP045817
Coordinates   4021044..4022246 (-) Length   400 a.a.
NCBI ID   WP_041850281.1    Uniprot ID   -
Organism   Bacillus subtilis strain P5_B1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4016044..4027246
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GII85_RS20495 (GII85_20495) rocE 4016276..4017679 (-) 1404 WP_003242721.1 amino acid permease -
  GII85_RS20500 (GII85_20500) rocD 4017902..4019107 (-) 1206 WP_041850283.1 ornithine aminotransferase -
  GII85_RS20505 (GII85_20505) rocR 4019348..4020733 (+) 1386 WP_041850282.1 arginine utilization regulatory protein RocR -
  GII85_RS20510 (GII85_20510) - 4020715..4020873 (-) 159 Protein_4005 ATP-binding protein -
  GII85_RS20515 (GII85_20515) - 4020895..4021024 (-) 130 Protein_4006 hypothetical protein -
  GII85_RS20520 (GII85_20520) htrA 4021044..4022246 (-) 1203 WP_041850281.1 serine protease HtrC Regulator
  GII85_RS20525 (GII85_20525) vicX 4022328..4023122 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  GII85_RS20530 (GII85_20530) walI 4023144..4023986 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  GII85_RS20535 (GII85_20535) walH 4023973..4025340 (-) 1368 WP_041850604.1 WalRK two-component regulatory system regulator WalH -
  GII85_RS20540 (GII85_20540) walK 4025330..4027165 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42760.53 Da        Isoelectric Point: 5.3441

>NTDB_id=346874 GII85_RS20520 WP_041850281.1 4021044..4022246(-) (htrA) [Bacillus subtilis strain P5_B1]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDNSAYVVTNHHVIEGASQIEISLKDGSRISAELVGSDQLMDL
AVLRVKSNKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=346874 GII85_RS20520 WP_041850281.1 4021044..4022246(-) (htrA) [Bacillus subtilis strain P5_B1]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTAAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGAAGCGGCTCAGGCGTCATCTATAAGAAAAATGACAACTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGCATATCAGCTGAACTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCAATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGCGAGCC
GGTTATTGCGATCGGGAATCCGTTAGGCCTTGAGTTTGCAGGTTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGGATTGAGATGAAATCGCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AATGTTACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(183-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.577

99.25

0.433
  htrA Streptococcus gordonii str. Challis substr. CH1

41.294

100

0.415
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373

Multiple sequence alignment