Detailed information    

insolico Bioinformatically predicted

Overview


Name   pilV/pilI   Type   Regulator
Locus tag   GHB96_RS02310 Genome accession   NZ_CP045707
Coordinates   448048..448656 (+) Length   202 a.a.
NCBI ID   WP_215772540.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain NG250     
Function   repress natural transformation; antagonize ComP (predicted from homology)   
Competence regulation

Genomic Context


Location: 443048..453656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GHB96_RS02285 (GHB96_02405) - 443483..443815 (+) 333 WP_003687908.1 hypothetical protein -
  GHB96_RS02290 (GHB96_02410) - 444146..444655 (+) 510 WP_003687909.1 isoprenylcysteine carboxyl methyltransferase family protein -
  GHB96_RS02295 (GHB96_02415) - 444896..445477 (-) 582 WP_003698180.1 superoxide dismutase -
  GHB96_RS02300 (GHB96_02420) dnaB 445640..447046 (+) 1407 WP_215772538.1 replicative DNA helicase -
  GHB96_RS02305 (GHB96_02425) pilH 447354..448016 (+) 663 WP_215772539.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  GHB96_RS02310 (GHB96_02430) pilV/pilI 448048..448656 (+) 609 WP_215772540.1 type IV pilus modification protein PilV Regulator
  GHB96_RS02315 (GHB96_02435) pilJ 448653..449588 (+) 936 WP_215772541.1 PilW family protein Machinery gene
  GHB96_RS02320 (GHB96_02440) pilK 449567..450166 (+) 600 WP_050157381.1 pilus assembly protein Machinery gene
  GHB96_RS02325 (GHB96_02445) pilL 450168..450641 (+) 474 WP_215772556.1 PilX family type IV pilin Machinery gene
  GHB96_RS02330 (GHB96_02450) - 450711..451019 (-) 309 WP_025456241.1 AzlD family protein -
  GHB96_RS02335 (GHB96_02455) - 451016..451727 (-) 712 Protein_459 AzlC family ABC transporter permease -
  GHB96_RS02340 (GHB96_02460) dut 451893..452345 (+) 453 WP_003687923.1 dUTP diphosphatase -
  GHB96_RS02345 (GHB96_02465) dapC 452423..453610 (+) 1188 WP_003687924.1 succinyldiaminopimelate transaminase -

Sequence


Protein


Download         Length: 202 a.a.        Molecular weight: 21902.83 Da        Isoelectric Point: 4.9738

>NTDB_id=345371 GHB96_RS02310 WP_215772540.1 448048..448656(+) (pilV/pilI) [Neisseria gonorrhoeae strain NG250]
MKNNDCLRLKNPQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKN
YNLYTGSYPLTSSDGDFKLNNLISKTDLAKAQLDRFGYELKQALPDAVAIHYAVCKDSSGGAPTLSGNTFSSNCDKKANG
DTLIKVLWVNDSAGDSDISRTNLEVSGDNIVYTYQARVGGRE

Nucleotide


Download         Length: 609 bp        

>NTDB_id=345371 GHB96_RS02310 WP_215772540.1 448048..448656(+) (pilV/pilI) [Neisseria gonorrhoeae strain NG250]
ATGAAGAATAATGATTGCTTGCGCCTGAAAAATCCCCAGTCCGGTATGGCGTTGATAGAAGTCTTGGTCGCTATGCTCGT
TCTGACCATCGGTATTTTGGCATTGCTGTCCGTACAGTTGCGGACAGTCGCTTCCGTCAGGGAGGCGGAGACACAAACCA
TCGTCAGCCAAATCACGCAAAACCTGATGGAAGGAATGTTGATGAATCCGACCATTGATTCGGACAGCAACAAGAAAAAC
TATAATCTTTACACGGGGTCGTACCCCCTCACTTCCTCTGACGGCGATTTCAAGCTTAATAATTTGATAAGTAAGACGGA
TTTGGCAAAAGCCCAGTTGGACAGGTTCGGTTATGAATTGAAACAAGCCTTGCCGGATGCGGTAGCTATTCATTACGCCG
TCTGCAAGGATTCGTCGGGTGGCGCGCCGACATTGTCCGGCAATACTTTTTCTTCAAATTGCGACAAGAAGGCAAACGGG
GATACTTTGATTAAAGTATTGTGGGTAAATGATTCGGCAGGGGATTCGGATATTTCCCGTACGAATCTTGAAGTGAGCGG
CGACAATATCGTATATACCTATCAGGCAAGGGTCGGAGGTCGTGAATGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilV/pilI Neisseria gonorrhoeae MS11

96.535

100

0.965

  pilV Neisseria meningitidis 8013

85.922

100

0.876


Multiple sequence alignment