Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SDEG_RS01690 Genome accession   NC_012891
Coordinates   318330..319091 (+) Length   253 a.a.
NCBI ID   WP_041788803.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis GGS_124     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 313330..324091
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDEG_RS01675 (SDEG_0344) - 313589..315157 (-) 1569 WP_041788800.1 ABC transporter substrate-binding protein/permease -
  SDEG_RS01680 (SDEG_0345) - 315356..317281 (+) 1926 WP_012766571.1 DUF2207 domain-containing protein -
  SDEG_RS01685 (SDEG_0346) - 317347..318186 (+) 840 WP_012766572.1 undecaprenyl-diphosphate phosphatase -
  SDEG_RS01690 (SDEG_0347) mecA 318330..319091 (+) 762 WP_041788803.1 adaptor protein MecA Regulator
  SDEG_RS01695 (SDEG_0348) - 319098..320267 (+) 1170 WP_003054822.1 glycosyltransferase family 4 protein -
  SDEG_RS01700 (SDEG_0349) sufC 320380..321150 (+) 771 WP_012766574.1 Fe-S cluster assembly ATPase SufC -
  SDEG_RS01705 (SDEG_0350) sufD 321246..322508 (+) 1263 WP_012766575.1 Fe-S cluster assembly protein SufD -
  SDEG_RS01710 (SDEG_0351) - 322539..323765 (+) 1227 WP_012766576.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29072.66 Da        Isoelectric Point: 4.0295

>NTDB_id=34368 SDEG_RS01690 WP_041788803.1 318330..319091(+) (mecA) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NEDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVGQEPELLDYVH
YVLDFATLSEAVAFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=34368 SDEG_RS01690 WP_041788803.1 318330..319091(+) (mecA) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGACCTACCAGACAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATGAGGACCTTAATCTTGAAGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
GGAACAATCTATGCGAGAAAAAGGGGATGTTAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGGTCAAGAACCAGAGCTGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCAGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAGCAACCATCTTATTTTGCCAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACCAGAGCTTACTTACAAGAGCATGGCGTACAATTGATTTTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.4

98.814

0.636
  mecA Streptococcus thermophilus LMD-9

57.831

98.419

0.569
  mecA Streptococcus thermophilus LMG 18311

57.028

98.419

0.561
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482

Multiple sequence alignment