Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EU512_RS08275 Genome accession   NZ_CP035541
Coordinates   1675731..1676597 (-) Length   288 a.a.
NCBI ID   WP_138109602.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain PK-01     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1657931..1706259 1675731..1676597 within 0


Gene organization within MGE regions


Location: 1657931..1706259
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EU512_RS08205 (EU512_08210) - 1659791..1661491 (-) 1701 WP_011275937.1 proline--tRNA ligase -
  EU512_RS08210 (EU512_08215) rseP 1661510..1662796 (-) 1287 WP_011275938.1 RIP metalloprotease RseP -
  EU512_RS08215 (EU512_08220) - 1663007..1663789 (-) 783 WP_011275939.1 phosphatidate cytidylyltransferase -
  EU512_RS08220 (EU512_08225) - 1663793..1664563 (-) 771 WP_011275940.1 isoprenyl transferase -
  EU512_RS08225 (EU512_08230) frr 1664789..1665343 (-) 555 WP_011275941.1 ribosome recycling factor -
  EU512_RS08230 (EU512_08235) pyrH 1665361..1666083 (-) 723 WP_011275942.1 UMP kinase -
  EU512_RS08235 (EU512_08240) tsf 1666220..1667098 (-) 879 WP_011275943.1 translation elongation factor Ts -
  EU512_RS08240 (EU512_08245) rpsB 1667256..1668044 (-) 789 WP_011275944.1 30S ribosomal protein S2 -
  EU512_RS08245 (EU512_08250) codY 1668311..1669084 (-) 774 WP_011275945.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  EU512_RS08250 (EU512_08255) hslU 1669106..1670509 (-) 1404 WP_011275946.1 ATP-dependent protease ATPase subunit HslU -
  EU512_RS08255 (EU512_08260) hslV 1670568..1671113 (-) 546 WP_011275947.1 ATP-dependent protease subunit HslV -
  EU512_RS08260 (EU512_08265) xerC 1671114..1672007 (-) 894 WP_011275948.1 tyrosine recombinase XerC -
  EU512_RS08265 (EU512_08270) trmFO 1672152..1673459 (-) 1308 WP_011275949.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  EU512_RS08270 (EU512_08275) topA 1673483..1675552 (-) 2070 WP_011275950.1 type I DNA topoisomerase -
  EU512_RS08275 (EU512_08280) dprA 1675731..1676597 (-) 867 WP_138109602.1 DNA-processing protein DprA Machinery gene
  EU512_RS08280 (EU512_08285) - 1676816..1678045 (-) 1230 WP_011275952.1 aminoacyltransferase -
  EU512_RS08285 (EU512_08290) sucD 1678345..1679250 (-) 906 WP_053026281.1 succinate--CoA ligase subunit alpha -
  EU512_RS08290 (EU512_08295) sucC 1679272..1680438 (-) 1167 WP_011275954.1 ADP-forming succinate--CoA ligase subunit beta -
  EU512_RS08295 (EU512_08300) - 1680550..1681317 (-) 768 WP_011275955.1 ribonuclease HII -
  EU512_RS08300 (EU512_08305) ylqF 1681301..1682185 (-) 885 WP_011275956.1 ribosome biogenesis GTPase YlqF -
  EU512_RS08305 (EU512_08310) - 1682423..1685017 (+) 2595 WP_053026282.1 YfhO family protein -
  EU512_RS08310 (EU512_08315) - 1685019..1687628 (+) 2610 WP_011275958.1 YfhO family protein -
  EU512_RS08315 (EU512_08320) rplS 1687785..1688135 (-) 351 WP_011275959.1 50S ribosomal protein L19 -
  EU512_RS08320 (EU512_08325) trmD 1688240..1688977 (-) 738 WP_011275960.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  EU512_RS08325 (EU512_08330) rimM 1688977..1689480 (-) 504 WP_053020112.1 ribosome maturation factor RimM -
  EU512_RS08330 (EU512_08335) rpsP 1689599..1689874 (-) 276 WP_011275962.1 30S ribosomal protein S16 -
  EU512_RS08335 (EU512_08340) ffh 1690121..1691491 (-) 1371 WP_011275963.1 signal recognition particle protein -
  EU512_RS08340 (EU512_08345) - 1691517..1691849 (-) 333 WP_011275964.1 putative DNA-binding protein -
  EU512_RS08345 (EU512_08350) ftsY 1691836..1693059 (-) 1224 WP_011275965.1 signal recognition particle-docking protein FtsY -
  EU512_RS08350 (EU512_08355) smc 1693056..1696625 (-) 3570 WP_016930692.1 chromosome segregation protein SMC -
  EU512_RS08355 (EU512_08360) rnc 1696710..1697447 (-) 738 WP_011275967.1 ribonuclease III -
  EU512_RS08360 (EU512_08365) - 1697533..1697766 (-) 234 WP_001830184.1 acyl carrier protein -
  EU512_RS08365 (EU512_08370) fabG 1697879..1698616 (-) 738 WP_011275968.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  EU512_RS08370 (EU512_08375) fabD 1698606..1699535 (-) 930 WP_011275969.1 ACP S-malonyltransferase -
  EU512_RS08375 (EU512_08380) plsX 1699528..1700514 (-) 987 WP_011275970.1 phosphate acyltransferase PlsX -
  EU512_RS08380 (EU512_08385) fapR 1700516..1701076 (-) 561 WP_011275971.1 transcription factor FapR -
  EU512_RS08385 (EU512_08390) recG 1701212..1703263 (-) 2052 WP_016930693.1 ATP-dependent DNA helicase RecG -
  EU512_RS08390 (EU512_08395) - 1703418..1704218 (-) 801 WP_011275973.1 thermonuclease family protein -
  EU512_RS08395 (EU512_08400) fakA 1704404..1706062 (-) 1659 WP_011275974.1 fatty acid kinase catalytic subunit FakA -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 33015.09 Da        Isoelectric Point: 9.2469

>NTDB_id=343091 EU512_RS08275 WP_138109602.1 1675731..1676597(-) (dprA) [Staphylococcus haemolyticus strain PK-01]
MTNNNILLLKLIWLGYTTQHIHHLLKLNPEFFKFSYTDQIDSIKNWDKLFHKGDFIDRYNHLNDKEILSFLNQHKISFVT
PFNANYPRLLKEIYDYPFVLFYQGDPQLLTSPNTLGVVGSRNATEYSAKAMQYLFPKFKQIPLTIISGLAKGADSIAHHF
AIEYQLPTIAVLGFGHMMHYPIETQKLRNIIEVKGLVISEYPPFTSVRRYHFPQRNRLISGLSQGVLITEASVRSGSQIT
IDCALDQNRNIYVLPGSIFNPLTKGNLKRAQEGAMIVTSADDILCDYK

Nucleotide


Download         Length: 867 bp        

>NTDB_id=343091 EU512_RS08275 WP_138109602.1 1675731..1676597(-) (dprA) [Staphylococcus haemolyticus strain PK-01]
ATGACTAACAACAACATATTACTTTTGAAATTAATTTGGTTAGGTTATACGACCCAACATATTCATCATTTATTAAAATT
AAATCCTGAATTTTTTAAATTCTCTTATACTGATCAAATAGATTCAATAAAAAATTGGGACAAGTTATTTCATAAAGGTG
ATTTTATTGATAGATATAATCATTTAAATGATAAAGAAATTTTGTCATTTTTGAATCAACACAAGATAAGTTTTGTAACA
CCGTTTAACGCTAATTATCCTCGACTATTAAAAGAAATTTATGATTATCCGTTTGTCCTATTTTACCAAGGTGACCCCCA
ATTATTAACATCCCCCAATACATTAGGTGTGGTGGGCTCAAGAAATGCAACAGAGTACTCAGCTAAAGCCATGCAATACT
TATTTCCTAAATTTAAACAAATTCCACTAACCATTATTTCCGGTTTGGCAAAAGGTGCTGATAGCATTGCACATCATTTT
GCTATAGAGTATCAATTACCTACTATAGCTGTTTTAGGTTTTGGTCATATGATGCATTACCCTATAGAAACGCAAAAATT
ACGCAACATAATTGAAGTAAAAGGTTTAGTTATTAGTGAATATCCGCCATTCACTAGTGTTAGGCGATATCACTTTCCGC
AACGCAATCGTTTGATAAGCGGTCTTTCACAAGGGGTTTTAATAACTGAAGCAAGTGTTAGAAGCGGTAGTCAAATTACA
ATTGATTGCGCATTAGACCAAAATAGAAATATATATGTATTACCAGGTTCAATATTTAATCCACTAACTAAAGGTAATTT
GAAACGAGCTCAAGAAGGTGCGATGATTGTAACCTCAGCTGATGATATTCTATGTGATTATAAATAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

49.825

98.958

0.493
  dprA Staphylococcus aureus N315

49.825

98.958

0.493
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae D39

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae R6

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

36.395

100

0.372
  dprA Streptococcus mutans UA159

37.544

98.958

0.372
  dprA/cilB/dalA Streptococcus mitis SK321

35.374

100

0.361

Multiple sequence alignment