Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ETT53_RS01490 Genome accession   NZ_CP035446
Coordinates   259556..260317 (+) Length   253 a.a.
NCBI ID   WP_129321494.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm68.2     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 254556..265317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT53_RS01475 (ETT53_01475) - 254814..256382 (-) 1569 WP_021340818.1 ABC transporter substrate-binding protein/permease -
  ETT53_RS01480 (ETT53_01480) - 256580..258505 (+) 1926 WP_014407295.1 DUF2207 domain-containing protein -
  ETT53_RS01485 (ETT53_01485) - 258571..259410 (+) 840 WP_002986031.1 undecaprenyl-diphosphate phosphatase -
  ETT53_RS01490 (ETT53_01490) mecA 259556..260317 (+) 762 WP_129321494.1 adaptor protein MecA Regulator
  ETT53_RS01495 (ETT53_01495) - 260324..261493 (+) 1170 WP_002991122.1 glycosyltransferase family 4 protein -
  ETT53_RS01500 (ETT53_01500) sufC 261615..262385 (+) 771 WP_011284505.1 Fe-S cluster assembly ATPase SufC -
  ETT53_RS01505 (ETT53_01505) sufD 262480..263742 (+) 1263 WP_129321493.1 Fe-S cluster assembly protein SufD -
  ETT53_RS01510 (ETT53_01510) - 263773..264999 (+) 1227 WP_011054183.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29109.76 Da        Isoelectric Point: 4.1444

>NTDB_id=342006 ETT53_RS01490 WP_129321494.1 259556..260317(+) (mecA) [Streptococcus pyogenes strain emm68.2]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEEADPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=342006 ETT53_RS01490 WP_129321494.1 259556..260317(+) (mecA) [Streptococcus pyogenes strain emm68.2]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGTTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAAAAAATTGAAGAGATAATGGAAGATGTTG
TTGAAGCTACTCTAGCTAATCAGTCTGAGGAGGCTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAATGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.2

98.814

0.625
  mecA Streptococcus thermophilus LMD-9

57.028

98.419

0.561
  mecA Streptococcus thermophilus LMG 18311

56.225

98.419

0.553
  mecA Streptococcus pneumoniae Rx1

48.235

100

0.486
  mecA Streptococcus pneumoniae D39

48.235

100

0.486
  mecA Streptococcus pneumoniae R6

48.235

100

0.486
  mecA Streptococcus pneumoniae TIGR4

48.235

100

0.486

Multiple sequence alignment