Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   ETT53_RS00795 Genome accession   NZ_CP035446
Coordinates   116369..117403 (+) Length   344 a.a.
NCBI ID   WP_261752453.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm68.2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 111369..122403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT53_RS00785 (ETT53_00785) - 115037..115402 (+) 366 WP_002986560.1 DUF1033 family protein -
  ETT53_RS00790 (ETT53_00790) comYA 115495..116433 (+) 939 WP_111684478.1 competence type IV pilus ATPase ComGA Machinery gene
  ETT53_RS00795 (ETT53_00795) comYB 116369..117403 (+) 1035 WP_261752453.1 competence type IV pilus assembly protein ComGB Machinery gene
  ETT53_RS00800 (ETT53_00800) comYC 117405..117731 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT53_RS00805 (ETT53_00805) comGD 117706..118134 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  ETT53_RS00810 (ETT53_00810) comGE 118091..118375 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  ETT53_RS00815 (ETT53_00815) comYF 118368..118802 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT53_RS00820 (ETT53_00820) comGG 118786..119112 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  ETT53_RS00825 (ETT53_00825) comYH 119210..120163 (+) 954 WP_038433850.1 class I SAM-dependent methyltransferase Machinery gene
  ETT53_RS00830 (ETT53_00830) - 120222..121418 (+) 1197 WP_129321437.1 acetate kinase -
  ETT53_RS00835 (ETT53_00835) - 121605..121913 (+) 309 Protein_116 hypothetical protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39713.21 Da        Isoelectric Point: 9.7085

>NTDB_id=341999 ETT53_RS00795 WP_261752453.1 116369..117403(+) (comYB) [Streptococcus pyogenes strain emm68.2]
MISFLRQDISIPSKLSLKKLSSKHQHKFIQLLANLLSTGFSFVEVIAFLKRSQLLQLDYVLKMEESLLKGQGLADMLSGL
GFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRRKTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLN
HFPAFFIGFCSGLILLFGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGHGLDLMTILDIMAIEKS
SLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELEIYAQESWEQFFSQLYQVTQLIQPAIFLV
VAVTIVMIYAAILLPIYQNMGGIF

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=341999 ETT53_RS00795 WP_261752453.1 116369..117403(+) (comYB) [Streptococcus pyogenes strain emm68.2]
TTGATCAGCTTTTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAGTAAACATCAGCATAA
ATTCATTCAATTACTAGCTAATCTTTTATCTACAGGATTTAGCTTCGTAGAGGTTATTGCTTTTTTAAAAAGAAGCCAGT
TGCTTCAGCTAGATTATGTTCTTAAAATGGAAGAGTCTTTATTAAAAGGACAAGGCTTAGCAGATATGTTGTCGGGTTTA
GGTTTTTCAGATGCTATTCTTACTCAAATTAGTTTAGCTGATAGACACGGTAATATTGAAACAACATTAGTAGCGATTCA
ACATTACTTGAACCAAATGGCAAGGATCAGACGAAAAACTGTTGAAGTTATCACCTATCCTCTTATTCTTTTACTTTTTC
TTTTTGTGATGATGCTAGGGTTGAGACGCTATTTAGTCCCTCAATTAGAAACTCAAAATCAGATAACTTACTTTCTTAAC
CATTTTCCTGCCTTCTTTATAGGTTTTTGCTCAGGTCTTATTTTGTTGTTCGGGATGGTATGGCTACGATGGCGATCTCA
AAGCCGCTTGAAACTCTATAGTCGGCTAAGCCGTTATCCTTTTTTAGGTAAACTGTTAAAACAATACTTAACTAGTTATT
ATGCTAGAGAATGGGGTACGTTAATAGGTCACGGTCTTGATTTGATGACTATTTTAGACATTATGGCCATTGAGAAATCC
TCACTAATGAAAGAATTAGCTGAGGACATCAGAATGAGTCTGCTTGAAGGGCAAGCCTTTCACATTAAAGTAGCTACCTA
CCCTTTTTTTAAAAAAGAATTAAGTTTAATGATTGAATACGGTGAAATCAAATCGAAACTGGGGGCTGAGTTGGAAATCT
ATGCCCAGGAAAGCTGGGAACAATTTTTTAGTCAGCTTTATCAAGTGACACAACTTATTCAACCAGCTATTTTTTTAGTA
GTTGCTGTGACAATCGTCATGATTTATGCGGCAATCCTATTACCAATTTACCAAAATATGGGAGGTATTTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(28-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

53.687

98.547

0.529
  comYB Streptococcus mutans UA159

53.687

98.547

0.529
  comYB Streptococcus gordonii str. Challis substr. CH1

50

98.837

0.494
  comGB/cglB Streptococcus mitis NCTC 12261

47.619

97.674

0.465
  comGB/cglB Streptococcus mitis SK321

47.748

96.802

0.462
  comGB/cglB Streptococcus pneumoniae Rx1

45.646

96.802

0.442
  comGB/cglB Streptococcus pneumoniae D39

45.646

96.802

0.442
  comGB/cglB Streptococcus pneumoniae R6

45.646

96.802

0.442
  comGB/cglB Streptococcus pneumoniae TIGR4

45.646

96.802

0.442
  comGB Lactococcus lactis subsp. cremoris KW2

42.462

94.477

0.401

Multiple sequence alignment