Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ETT55_RS08775 Genome accession   NZ_CP035444
Coordinates   1762649..1763872 (+) Length   407 a.a.
NCBI ID   WP_136021706.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm90.5     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1757649..1768872
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT55_RS08760 (ETT55_08755) - 1760789..1761563 (-) 775 Protein_1624 IS30 family transposase -
  ETT55_RS08770 (ETT55_08765) rlmH 1761958..1762437 (-) 480 WP_002981964.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ETT55_RS08775 (ETT55_08770) htrA 1762649..1763872 (+) 1224 WP_136021706.1 S1C family serine protease Regulator
  ETT55_RS08780 (ETT55_08775) spo0J 1763961..1764737 (+) 777 WP_168388899.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 42786.41 Da        Isoelectric Point: 7.3103

>NTDB_id=341938 ETT55_RS08775 WP_136021706.1 1762649..1763872(+) (htrA) [Streptococcus pyogenes strain emm90.5]
MPSMKHILKSLSILLIGFLGGLIAIITFNNLYPYSPSKINSGKATTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSS
SLSNPYTKLFGEGRSKENKDAELSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGIGFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQ
INIPTSVTGGIVVAEVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKADIKLTKTT
QDLTKTQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=341938 ETT55_RS08775 WP_136021706.1 1762649..1763872(+) (htrA) [Streptococcus pyogenes strain emm90.5]
ATGCCAAGTATGAAACATATCTTAAAATCCTTAAGTATTTTACTAATTGGATTTTTAGGAGGATTAATAGCAATTATTAC
ATTCAATAATCTCTACCCATATTCTCCATCAAAAATAAATTCAGGTAAGGCAACAACTAGTAATATGGTTTTTAACAACA
CAACCAATACTACTAAAGCTGTCAAAGCTGTTCAAAATGCAGTTGTATCAGTTATTAATTATCAAGATAACCCTTCTTCA
TCCCTTTCTAACCCTTATACAAAACTCTTTGGAGAAGGGCGTTCAAAAGAGAATAAGGATGCTGAATTATCTATTTTTAG
TGAAGGATCTGGGGTCATTTATCGAAAAGATGGCAACTCCGCTTACGTTGTTACTAATAACCATGTTATCGACGGAGCTA
AACGAATTGAAATTCTTATGGCAGACGGATCTAAAGTTGTTGGTGAATTAGTTGGAGCTGATACTTATTCGGATTTAGCT
GTTGTTAAGATCTCTTCAGATAAGATAAAAACAGTAGCTGAATTTGCAGATTCTACAAAACTAAATGTTGGAGAAGTTGC
TATTGCTATCGGCAGCCCACTAGGAACACAATACGCTAATTCTGTTACTCAAGGAATCGTCTCTAGTTTAAGTCGTACTG
TAACTTTAAAAAACGAGAATGGTGAGACTGTCTCAACAAATGCTATTCAGACAGATGCTGCTATTAACCCTGGAAACTCT
GGTGGACCACTAATTAATATTGAGGGGCAAGTAATCGGAATTAATTCAAGTAAAATTTCTTCTACCCCAACTGGTAGCAA
CGGTAATAGTGGTGCTGTTGAAGGAATTGGTTTTGCTATCCCATCTACTGATGTTATTAAAATTATTAAACAACTAGAAA
CTAATGGTGAAGTTATCAGACCTGCTCTTGGAATATCCATGGTCAATTTAAATGACTTATCCACAAATGCTCTTAGTCAA
ATTAATATTCCAACTAGTGTAACTGGTGGTATTGTAGTAGCAGAAGTTAAGGAAGGAATGCCGGCATCTGGCAAACTTGC
TCAGTACGATGTGATTACAGAAATTGATGGCAAAACAGTTAATTCAATTAGTGATTTACAAAGTAGTCTATACGGACACG
ATATTAATGATACTATTAAAGTAACTTTTTATAGAGGAACTACAAAGAAAAAAGCAGATATCAAATTAACAAAAACTACT
CAAGATTTGACTAAAACGCAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(301-396)

Trypsin-like peptidase domain (Trypsin_2)

(109-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.881

99.263

0.614
  htrA Streptococcus gordonii str. Challis substr. CH1

54.975

98.771

0.543
  htrA Streptococcus mitis NCTC 12261

53.071

100

0.531
  htrA Streptococcus pneumoniae Rx1

52.826

100

0.528
  htrA Streptococcus pneumoniae D39

52.826

100

0.528
  htrA Streptococcus pneumoniae R6

52.826

100

0.528
  htrA Streptococcus pneumoniae TIGR4

52.826

100

0.528

Multiple sequence alignment