Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ETT55_RS01505 Genome accession   NZ_CP035444
Coordinates   268960..269721 (+) Length   253 a.a.
NCBI ID   WP_136021766.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm90.5     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 263960..274721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT55_RS01490 (ETT55_01490) - 264219..265787 (-) 1569 WP_136021765.1 ABC transporter substrate-binding protein/permease -
  ETT55_RS01495 (ETT55_01495) - 265985..267909 (+) 1925 Protein_239 DUF2207 domain-containing protein -
  ETT55_RS01500 (ETT55_01500) - 267975..268814 (+) 840 WP_002986031.1 undecaprenyl-diphosphate phosphatase -
  ETT55_RS01505 (ETT55_01505) mecA 268960..269721 (+) 762 WP_136021766.1 adaptor protein MecA Regulator
  ETT55_RS01510 (ETT55_01510) - 269728..270897 (+) 1170 WP_002991122.1 glycosyltransferase family 4 protein -
  ETT55_RS01515 (ETT55_01515) sufC 271019..271789 (+) 771 WP_002986023.1 Fe-S cluster assembly ATPase SufC -
  ETT55_RS01520 (ETT55_01520) sufD 271884..273146 (+) 1263 WP_047235146.1 Fe-S cluster assembly protein SufD -
  ETT55_RS01525 (ETT55_01525) - 273177..274403 (+) 1227 WP_010921888.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29069.76 Da        Isoelectric Point: 4.1622

>NTDB_id=341898 ETT55_RS01505 WP_136021766.1 268960..269721(+) (mecA) [Streptococcus pyogenes strain emm90.5]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEMMEDVVEATLANQSEAADPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=341898 ETT55_RS01505 WP_136021766.1 268960..269721(+) (mecA) [Streptococcus pyogenes strain emm90.5]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGTTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAAAAAATTGAAGAGATGATGGAAGATGTTG
TTGAAGCTACTCTAGCTAATCAGTCTGAGGCGGCTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAATGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.4

98.814

0.636
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.422

98.419

0.545
  mecA Streptococcus pneumoniae Rx1

48.235

100

0.486
  mecA Streptococcus pneumoniae D39

48.235

100

0.486
  mecA Streptococcus pneumoniae R6

48.235

100

0.486
  mecA Streptococcus pneumoniae TIGR4

48.235

100

0.486

Multiple sequence alignment