Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ETT59_RS01385 Genome accession   NZ_CP035440
Coordinates   250598..251359 (+) Length   253 a.a.
NCBI ID   WP_136305998.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm124     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 245598..256359
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT59_RS01370 (ETT59_01370) - 245857..247425 (-) 1569 WP_053308187.1 ABC transporter substrate-binding protein/permease -
  ETT59_RS01375 (ETT59_01375) - 247598..249547 (+) 1950 Protein_217 DUF2207 family protein -
  ETT59_RS01380 (ETT59_01380) - 249613..250452 (+) 840 WP_002986031.1 undecaprenyl-diphosphate phosphatase -
  ETT59_RS01385 (ETT59_01385) mecA 250598..251359 (+) 762 WP_136305998.1 adaptor protein MecA Regulator
  ETT59_RS01390 (ETT59_01390) - 251366..252535 (+) 1170 WP_136107481.1 glycosyltransferase family 4 protein -
  ETT59_RS01395 (ETT59_01395) sufC 252657..253427 (+) 771 WP_002986023.1 Fe-S cluster assembly ATPase SufC -
  ETT59_RS01400 (ETT59_01400) sufD 253522..254784 (+) 1263 WP_053308190.1 Fe-S cluster assembly protein SufD -
  ETT59_RS01405 (ETT59_01405) - 254815..256041 (+) 1227 WP_136276571.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29081.75 Da        Isoelectric Point: 4.1622

>NTDB_id=341682 ETT59_RS01385 WP_136305998.1 250598..251359(+) (mecA) [Streptococcus pyogenes strain emm124]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEATDPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=341682 ETT59_RS01385 WP_136305998.1 250598..251359(+) (mecA) [Streptococcus pyogenes strain emm124]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGTTTTCGAGTGACTCCACGCAAAGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAAAAAATTGAAGAGATAATGGAAGATGTTG
TTGAAGCCACTCTAGCTAATCAGTCTGAGGCGACTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAATGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.6

98.814

0.628
  mecA Streptococcus thermophilus LMD-9

56.175

99.209

0.557
  mecA Streptococcus thermophilus LMG 18311

55.378

99.209

0.549
  mecA Streptococcus pneumoniae Rx1

48.235

100

0.486
  mecA Streptococcus pneumoniae D39

48.235

100

0.486
  mecA Streptococcus pneumoniae R6

48.235

100

0.486
  mecA Streptococcus pneumoniae TIGR4

48.235

100

0.486

Multiple sequence alignment