Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ETT72_RS01650 Genome accession   NZ_CP035427
Coordinates   289956..290717 (+) Length   253 a.a.
NCBI ID   WP_032464171.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm74     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 284956..295717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT72_RS01635 (ETT72_01635) - 285214..286782 (-) 1569 WP_032464169.1 ABC transporter substrate-binding protein/permease -
  ETT72_RS01640 (ETT72_01640) - 286980..288905 (+) 1926 WP_136284064.1 DUF2207 domain-containing protein -
  ETT72_RS01645 (ETT72_01645) - 288971..289810 (+) 840 WP_136292363.1 undecaprenyl-diphosphate phosphatase -
  ETT72_RS01650 (ETT72_01650) mecA 289956..290717 (+) 762 WP_032464171.1 adaptor protein MecA Regulator
  ETT72_RS01655 (ETT72_01655) - 290724..291893 (+) 1170 WP_002991122.1 glycosyltransferase family 4 protein -
  ETT72_RS01660 (ETT72_01660) sufC 292015..292785 (+) 771 WP_002986023.1 Fe-S cluster assembly ATPase SufC -
  ETT72_RS01665 (ETT72_01665) sufD 292880..294142 (+) 1263 WP_023612423.1 Fe-S cluster assembly protein SufD -
  ETT72_RS01670 (ETT72_01670) - 294173..295399 (+) 1227 WP_002991117.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 28998.67 Da        Isoelectric Point: 4.1282

>NTDB_id=340986 ETT72_RS01650 WP_032464171.1 289956..290717(+) (mecA) [Streptococcus pyogenes strain emm74]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQMTPEDFFKSLEQSMCEKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=340986 ETT72_RS01650 WP_032464171.1 289956..290717(+) (mecA) [Streptococcus pyogenes strain emm74]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGCTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGTGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAAAAAATTGAAGAGATAATGGAAGATGTTG
TTGAAGCCACTCTAGCTAATCAGTCTGAGGCGGCTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAATGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

62.8

98.814

0.621
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.422

98.419

0.545
  mecA Streptococcus pneumoniae Rx1

47.431

100

0.474
  mecA Streptococcus pneumoniae D39

47.431

100

0.474
  mecA Streptococcus pneumoniae R6

47.431

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.431

100

0.474

Multiple sequence alignment