Detailed information NTG0339151

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: ESP48_RS00895
• Genome accession: NZ_CP035306
• Coordinates: 160568..161275 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain IDCC2201
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 155568..166275

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ESP48_RS00870 (ESP48_00870)	yidA	155919..156728 (+)	810	WP_011226081.1	sugar-phosphatase	-
ESP48_RS00875 (ESP48_00875)	-	156730..157944 (+)	1215	WP_002953123.1	aminoacyltransferase	-
ESP48_RS00880 (ESP48_00880)	-	157996..158357 (-)	362	Protein_164	YbaN family protein	-
ESP48_RS00885 (ESP48_00885)	vicX	158417..159226 (-)	810	WP_024704147.1	MBL fold metallo-hydrolase	Regulator
ESP48_RS00890 (ESP48_00890)	vicK	159235..160575 (-)	1341	WP_014621665.1	cell wall metabolism sensor histidine kinase VicK	Regulator
ESP48_RS00895 (ESP48_00895)	vicR	160568..161275 (-)	708	WP_011681206.1	response regulator YycF	Regulator
ESP48_RS00900 (ESP48_00900)	-	161801..162568 (+)	768	WP_064355894.1	amino acid ABC transporter ATP-binding protein	-
ESP48_RS00905 (ESP48_00905)	-	162580..163413 (+)	834	WP_002953142.1	transporter substrate-binding domain-containing protein	-
ESP48_RS00910 (ESP48_00910)	-	163431..164129 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
ESP48_RS00915 (ESP48_00915)	-	164141..164791 (+)	651	WP_064355893.1	amino acid ABC transporter permease	-
ESP48_RS00920 (ESP48_00920)	endA	164862..165743 (-)	882	WP_014621666.1	DNA/RNA non-specific endonuclease	Machinery gene
ESP48_RS00925 (ESP48_00925)	-	165805..165993 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=339151 ESP48_RS00895 WP_011681206.1 160568..161275(-) (vicR) [Streptococcus thermophilus strain IDCC2201]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=339151 ESP48_RS00895 WP_011681206.1 160568..161275(-) (vicR) [Streptococcus thermophilus strain IDCC2201]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387