Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   EQH20_RS00220 Genome accession   NZ_CP035260
Coordinates   41812..43161 (+) Length   449 a.a.
NCBI ID   WP_000801608.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901925     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 36812..48161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH20_RS00195 (EQH20_00205) plsX 36931..37923 (+) 993 WP_000717458.1 phosphate acyltransferase PlsX -
  EQH20_RS00200 (EQH20_00210) - 37929..38162 (+) 234 WP_000136447.1 acyl carrier protein -
  EQH20_RS00205 (EQH20_00215) - 38199..38498 (+) 300 Protein_34 transposase family protein -
  EQH20_RS00210 (EQH20_00220) blpU 38701..38931 (+) 231 WP_001093075.1 bacteriocin-like peptide BlpU -
  EQH20_RS10195 - 38934..39059 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  EQH20_RS00215 (EQH20_00225) comA 39646..41799 (+) 2154 WP_000668301.1 peptide cleavage/export ABC transporter ComA Regulator
  EQH20_RS00220 (EQH20_00230) comB 41812..43161 (+) 1350 WP_000801608.1 competence pheromone export protein ComB Regulator
  EQH20_RS00225 (EQH20_00235) purC 43331..44038 (+) 708 WP_000043304.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  EQH20_RS10240 (EQH20_00240) - 44049..44159 (+) 111 WP_078065395.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  EQH20_RS00230 (EQH20_00245) - 44240..47965 (+) 3726 WP_061647516.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49601.44 Da        Isoelectric Point: 5.3895

>NTDB_id=338284 EQH20_RS00220 WP_000801608.1 41812..43161(+) (comB) [Streptococcus pneumoniae strain TVO_1901925]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=338284 EQH20_RS00220 WP_000801608.1 41812..43161(+) (comB) [Streptococcus pneumoniae strain TVO_1901925]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATTCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTTTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

99.332

100

0.993
  comB Streptococcus pneumoniae Rx1

99.109

100

0.991
  comB Streptococcus pneumoniae D39

99.109

100

0.991
  comB Streptococcus pneumoniae R6

99.109

100

0.991
  comB Streptococcus mitis SK321

94.878

100

0.949
  comB Streptococcus mitis NCTC 12261

94.432

100

0.944
  comB Streptococcus gordonii str. Challis substr. CH1

55.333

100

0.555

Multiple sequence alignment