Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   EQH21_RS10400 Genome accession   NZ_CP035259
Coordinates   2045508..2046170 (-) Length   220 a.a.
NCBI ID   WP_000649963.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901926     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2040508..2051170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH21_RS10375 (EQH21_10890) - 2040658..2040924 (-) 267 WP_001278167.1 Veg family protein -
  EQH21_RS10380 (EQH21_10895) dnaB 2040926..2042278 (-) 1353 WP_000852499.1 replicative DNA helicase -
  EQH21_RS10385 (EQH21_10900) rplI 2042322..2042774 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  EQH21_RS10390 (EQH21_10905) - 2042771..2044744 (-) 1974 WP_000715111.1 DHH family phosphoesterase -
  EQH21_RS10395 (EQH21_10910) hpf 2044880..2045428 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EQH21_RS10400 (EQH21_10915) comFC/cflB 2045508..2046170 (-) 663 WP_000649963.1 ComF family protein Machinery gene
  EQH21_RS10405 (EQH21_10920) comFA/cflA 2046167..2047465 (-) 1299 WP_000867608.1 DEAD/DEAH box helicase Machinery gene
  EQH21_RS10410 (EQH21_10925) - 2047521..2048156 (+) 636 WP_000395729.1 YigZ family protein -
  EQH21_RS10415 (EQH21_10935) cysK 2048441..2049361 (+) 921 WP_000029877.1 cysteine synthase A -
  EQH21_RS10420 (EQH21_10945) - 2049600..2049950 (-) 351 Protein_2043 IS66 family transposase -
  EQH21_RS10425 (EQH21_10950) - 2049950..2050242 (+) 293 Protein_2044 transposase -
  EQH21_RS10430 (EQH21_10955) tnpB 2050383..2050706 (-) 324 WP_000973414.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25180.10 Da        Isoelectric Point: 7.3688

>NTDB_id=338271 EQH21_RS10400 WP_000649963.1 2045508..2046170(-) (comFC/cflB) [Streptococcus pneumoniae strain TVO_1901926]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSIKCQDCQLLCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=338271 EQH21_RS10400 WP_000649963.1 2045508..2046170(-) (comFC/cflB) [Streptococcus pneumoniae strain TVO_1901926]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAATAAAGTGTCAAGATTGTCAACTTTTGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae Rx1

98.636

100

0.986
  comFC/cflB Streptococcus pneumoniae D39

98.636

100

0.986
  comFC/cflB Streptococcus pneumoniae R6

98.636

100

0.986
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.455

100

0.905

Multiple sequence alignment