Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   EQH21_RS09540 Genome accession   NZ_CP035259
Coordinates   1870683..1870985 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901926     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1865683..1875985
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH21_RS09510 (EQH21_09990) rnpA 1866363..1866734 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EQH21_RS10675 - 1866751..1866882 (-) 132 WP_000768904.1 hypothetical protein -
  EQH21_RS09515 (EQH21_09995) - 1866883..1868073 (-) 1191 WP_000167769.1 acetate kinase -
  EQH21_RS09520 (EQH21_10000) comYH 1868124..1869077 (-) 954 WP_000345127.1 class I SAM-dependent methyltransferase Machinery gene
  EQH21_RS09525 (EQH21_10005) - 1869138..1869732 (-) 595 Protein_1880 class I SAM-dependent methyltransferase -
  EQH21_RS09530 (EQH21_10010) comGG/cglG 1869835..1870281 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH21_RS09535 (EQH21_10015) comGF/cglF 1870259..1870720 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH21_RS09540 (EQH21_10020) comGE/cglE 1870683..1870985 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH21_RS09545 (EQH21_10025) comGD/cglD 1870948..1871352 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH21_RS09550 (EQH21_10030) comGC/cglC 1871345..1871671 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  EQH21_RS09555 (EQH21_10035) comGB/cglB 1871673..1872689 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH21_RS09560 (EQH21_10040) comGA/cglA/cilD 1872637..1873578 (-) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH21_RS09565 (EQH21_10045) - 1873653..1874018 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH21_RS09570 (EQH21_10050) - 1874169..1875227 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=338260 EQH21_RS09540 WP_000413382.1 1870683..1870985(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901926]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=338260 EQH21_RS09540 WP_000413382.1 1870683..1870985(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901926]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment