Detailed information NTG0338259

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EQH21_RS09535
• Genome accession: NZ_CP035259
• Coordinates: 1870259..1870720 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901926
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1865259..1875720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH21_RS09505 (EQH21_09985)	-	1865564..1866388 (-)	825	WP_000727909.1	membrane protein insertase YidC	-
EQH21_RS09510 (EQH21_09990)	rnpA	1866363..1866734 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH21_RS10675	-	1866751..1866882 (-)	132	WP_000768904.1	hypothetical protein	-
EQH21_RS09515 (EQH21_09995)	-	1866883..1868073 (-)	1191	WP_000167769.1	acetate kinase	-
EQH21_RS09520 (EQH21_10000)	comYH	1868124..1869077 (-)	954	WP_000345127.1	class I SAM-dependent methyltransferase	Machinery gene
EQH21_RS09525 (EQH21_10005)	-	1869138..1869732 (-)	595	Protein_1880	class I SAM-dependent methyltransferase	-
EQH21_RS09530 (EQH21_10010)	comGG/cglG	1869835..1870281 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH21_RS09535 (EQH21_10015)	comGF/cglF	1870259..1870720 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH21_RS09540 (EQH21_10020)	comGE/cglE	1870683..1870985 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH21_RS09545 (EQH21_10025)	comGD/cglD	1870948..1871352 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH21_RS09550 (EQH21_10030)	comGC/cglC	1871345..1871671 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
EQH21_RS09555 (EQH21_10035)	comGB/cglB	1871673..1872689 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH21_RS09560 (EQH21_10040)	comGA/cglA/cilD	1872637..1873578 (-)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH21_RS09565 (EQH21_10045)	-	1873653..1874018 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH21_RS09570 (EQH21_10050)	-	1874169..1875227 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=338259 EQH21_RS09535 WP_000250539.1 1870259..1870720(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901926]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=338259 EQH21_RS09535 WP_000250539.1 1870259..1870720(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901926]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915