Detailed information NTG0338184

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: EQH22_RS09800
• Genome accession: NZ_CP035258
• Coordinates: 1909740..1910042 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901927
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1904740..1915042

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH22_RS09770 (EQH22_10265)	rnpA	1905420..1905791 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH22_RS10940	-	1905808..1905939 (-)	132	WP_000768904.1	hypothetical protein	-
EQH22_RS09775 (EQH22_10270)	-	1905940..1907130 (-)	1191	WP_000167769.1	acetate kinase	-
EQH22_RS09780 (EQH22_10275)	comYH	1907181..1908134 (-)	954	WP_000345127.1	class I SAM-dependent methyltransferase	Machinery gene
EQH22_RS09785 (EQH22_10280)	-	1908195..1908789 (-)	595	Protein_1934	class I SAM-dependent methyltransferase	-
EQH22_RS09790 (EQH22_10285)	comGG/cglG	1908892..1909338 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH22_RS09795 (EQH22_10290)	comGF/cglF	1909316..1909777 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH22_RS09800 (EQH22_10295)	comGE/cglE	1909740..1910042 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH22_RS09805 (EQH22_10300)	comGD/cglD	1910005..1910409 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH22_RS09810 (EQH22_10305)	comGC/cglC	1910402..1910728 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
EQH22_RS09815 (EQH22_10310)	comGB/cglB	1910730..1911746 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH22_RS09820 (EQH22_10315)	comGA/cglA/cilD	1911694..1912635 (-)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH22_RS09825 (EQH22_10320)	-	1912710..1913075 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH22_RS09830 (EQH22_10325)	-	1913226..1914284 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=338184 EQH22_RS09800 WP_000413382.1 1909740..1910042(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901927]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=338184 EQH22_RS09800 WP_000413382.1 1909740..1910042(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901927]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4