Detailed information NTG0338106

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EQH23_RS09995
• Genome accession: NZ_CP035257
• Coordinates: 1952882..1953343 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901928
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1947882..1958343

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH23_RS09965 (EQH23_10565)	-	1948189..1949013 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
EQH23_RS09970 (EQH23_10570)	rnpA	1948988..1949359 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH23_RS11110	-	1949376..1949507 (-)	132	WP_000768904.1	hypothetical protein	-
EQH23_RS09975 (EQH23_10575)	-	1949508..1950698 (-)	1191	WP_000167765.1	acetate kinase	-
EQH23_RS09980 (EQH23_10580)	comYH	1950749..1951702 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
EQH23_RS09985 (EQH23_10585)	-	1951763..1952355 (-)	593	Protein_1966	class I SAM-dependent methyltransferase	-
EQH23_RS09990 (EQH23_10590)	comGG/cglG	1952458..1952904 (-)	447	WP_001809944.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH23_RS09995 (EQH23_10595)	comGF/cglF	1952882..1953343 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH23_RS10000 (EQH23_10600)	comGE/cglE	1953306..1953608 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH23_RS10005 (EQH23_10605)	comGD/cglD	1953571..1954005 (-)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH23_RS10010 (EQH23_10610)	comGC/cglC	1953968..1954291 (-)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
EQH23_RS10015 (EQH23_10615)	comGB/cglB	1954293..1955309 (-)	1017	WP_078130737.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH23_RS10020 (EQH23_10620)	comGA/cglA/cilD	1955257..1956198 (-)	942	WP_000249536.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH23_RS10025 (EQH23_10625)	-	1956274..1956639 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH23_RS10030 (EQH23_10630)	-	1956790..1957848 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=338106 EQH23_RS09995 WP_000250531.1 1952882..1953343(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901928]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=338106 EQH23_RS09995 WP_000250531.1 1952882..1953343(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901928]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915