Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   EQH23_RS09980 Genome accession   NZ_CP035257
Coordinates   1950749..1951702 (-) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain TVO_1901928     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1945749..1956702
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH23_RS09955 (EQH23_10555) - 1946510..1947133 (-) 624 WP_000932658.1 hypothetical protein -
  EQH23_RS09960 (EQH23_10560) jag 1947184..1948170 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  EQH23_RS09965 (EQH23_10565) - 1948189..1949013 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  EQH23_RS09970 (EQH23_10570) rnpA 1948988..1949359 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EQH23_RS11110 - 1949376..1949507 (-) 132 WP_000768904.1 hypothetical protein -
  EQH23_RS09975 (EQH23_10575) - 1949508..1950698 (-) 1191 WP_000167765.1 acetate kinase -
  EQH23_RS09980 (EQH23_10580) comYH 1950749..1951702 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  EQH23_RS09985 (EQH23_10585) - 1951763..1952355 (-) 593 Protein_1966 class I SAM-dependent methyltransferase -
  EQH23_RS09990 (EQH23_10590) comGG/cglG 1952458..1952904 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH23_RS09995 (EQH23_10595) comGF/cglF 1952882..1953343 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH23_RS10000 (EQH23_10600) comGE/cglE 1953306..1953608 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH23_RS10005 (EQH23_10605) comGD/cglD 1953571..1954005 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH23_RS10010 (EQH23_10610) comGC/cglC 1953968..1954291 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  EQH23_RS10015 (EQH23_10615) comGB/cglB 1954293..1955309 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH23_RS10020 (EQH23_10620) comGA/cglA/cilD 1955257..1956198 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH23_RS10025 (EQH23_10625) - 1956274..1956639 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=338104 EQH23_RS09980 WP_000345126.1 1950749..1951702(-) (comYH) [Streptococcus pneumoniae strain TVO_1901928]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=338104 EQH23_RS09980 WP_000345126.1 1950749..1951702(-) (comYH) [Streptococcus pneumoniae strain TVO_1901928]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment