Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE/cglE   Type   Machinery gene
Locus tag   EQH24_RS10205 Genome accession   NZ_CP035256
Coordinates   1967233..1967535 (-) Length   100 a.a.
NCBI ID   WP_256901086.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901930     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1962233..1972535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH24_RS10175 (EQH24_10700) rnpA 1962912..1963283 (-) 372 WP_000739244.1 ribonuclease P protein component -
  EQH24_RS11675 - 1963300..1963431 (-) 132 WP_000768904.1 hypothetical protein -
  EQH24_RS10180 (EQH24_10705) - 1963432..1964622 (-) 1191 WP_000167753.1 acetate kinase -
  EQH24_RS10185 (EQH24_10710) comYH 1964673..1965626 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  EQH24_RS10190 (EQH24_10715) - 1965687..1966281 (-) 595 Protein_2013 class I SAM-dependent methyltransferase -
  EQH24_RS10195 (EQH24_10720) comGG/cglG 1966418..1966831 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH24_RS10200 (EQH24_10725) comGF/cglF 1966809..1967270 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH24_RS10205 (EQH24_10730) comGE/cglE 1967233..1967535 (-) 303 WP_256901086.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH24_RS10210 (EQH24_10735) comGD/cglD 1967498..1967902 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH24_RS10215 (EQH24_10740) comGC/cglC 1967895..1968161 (-) 267 WP_050129046.1 competence type IV pilus major pilin ComGC Machinery gene
  EQH24_RS10220 (EQH24_10745) - 1968163..1968420 (-) 258 WP_238101663.1 hypothetical protein -
  EQH24_RS10225 (EQH24_10750) - 1968652..1969608 (-) 957 WP_000350480.1 N-acetylmuramoyl-L-alanine amidase family protein -
  EQH24_RS10230 (EQH24_10755) - 1969612..1969944 (-) 333 WP_001186219.1 phage holin -
  EQH24_RS10235 (EQH24_10760) - 1969948..1970247 (-) 300 WP_001811580.1 hypothetical protein -
  EQH24_RS10240 (EQH24_10765) - 1970256..1970606 (-) 351 WP_000852245.1 hypothetical protein -
  EQH24_RS10245 (EQH24_10770) - 1970609..1970812 (-) 204 WP_001091123.1 hypothetical protein -
  EQH24_RS10250 (EQH24_10775) - 1970793..1970909 (-) 117 WP_001063632.1 hypothetical protein -

Sequence


Protein


Download         Length: 100 a.a.        Molecular weight: 11180.15 Da        Isoelectric Point: 8.5847

>NTDB_id=338026 EQH24_RS10205 WP_256901086.1 1967233..1967535(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901930]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLEQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=338026 EQH24_RS10205 WP_256901086.1 1967233..1967535(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901930]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGAACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99

  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99

  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99

  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99

  comGE/cglE Streptococcus mitis NCTC 12261

97

100

0.97

  comGE/cglE Streptococcus mitis SK321

97

100

0.97

  comYE Streptococcus mutans UA140

44.444

90

0.4

  comYE Streptococcus mutans UA159

44.444

90

0.4


Multiple sequence alignment