Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FTN78_RS06495 Genome accession   NZ_CP043523
Coordinates   1259623..1260993 (-) Length   456 a.a.
NCBI ID   WP_010906089.1    Uniprot ID   Q9CF07
Organism   Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1254623..1265993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FTN78_RS06480 (FTN78_chr1281) - 1255794..1257227 (-) 1434 WP_010906086.1 6-phospho-beta-glucosidase -
  FTN78_RS06485 (FTN78_chr1282) yidD 1257350..1257616 (-) 267 WP_010906087.1 membrane protein insertion efficiency factor YidD -
  FTN78_RS06490 (FTN78_chr1283) - 1257733..1259475 (-) 1743 WP_010906088.1 1-deoxy-D-xylulose-5-phosphate synthase -
  FTN78_RS06495 (FTN78_chr1284) ciaH 1259623..1260993 (-) 1371 WP_010906089.1 cell wall metabolism sensor histidine kinase WalK Regulator
  FTN78_RS06500 (FTN78_chr1285) ciaR 1261086..1261754 (-) 669 WP_021722129.1 response regulator transcription factor Regulator
  FTN78_RS06505 (FTN78_chr1286) - 1261932..1262906 (-) 975 WP_003130365.1 LacI family DNA-binding transcriptional regulator -
  FTN78_RS06510 (FTN78_chr1287) - 1263059..1265314 (-) 2256 WP_010906090.1 glycoside hydrolase family 65 protein -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51278.80 Da        Isoelectric Point: 9.3135

>NTDB_id=338024 FTN78_RS06495 WP_010906089.1 1259623..1260993(-) (ciaH) [Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96]
MKKIIKKVKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLIEAANNQLGMNNSQD
SGYYGPNNSVIFYDSEGKSFIPSAGSNANISTNFGMSLLQKTMKFNENQINTIQTVSVKNPYGDNWHYRYLTTSQFIITN
TDGTVTPVYAQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSVIISLYLANWTLKPILAAYEKQKEFVENASHELRTPLAI
LQNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKF
SGDLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKART
RQKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=338024 FTN78_RS06495 WP_010906089.1 1259623..1260993(-) (ciaH) [Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96]
TTGAAGAAAATAATTAAAAAAGTTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTCTTTTTGATAGAAGCAGCGAATAATCAATTAGGAATGAATAATTCGCAAGAT
AGTGGCTATTACGGTCCCAATAATAGTGTAATTTTTTATGATTCAGAGGGTAAAAGTTTCATACCTTCAGCGGGTTCAAA
TGCAAATATAAGTACAAATTTTGGCATGAGCCTTCTGCAAAAAACAATGAAATTTAACGAAAATCAAATTAACACTATTC
AAACTGTTTCTGTAAAAAATCCTTATGGAGATAATTGGCACTATCGTTATCTGACAACATCACAATTTATTATTACAAAT
ACTGATGGAACAGTAACTCCGGTTTATGCACAAATTTTTTCAAATGTTGACCAAATTCAAGATGCCATGAGCCGAGCCAT
GTGGGTCATTGTGACAACAATGATTACTTTCTGGCTTCTGTCAGTAATTATTAGTCTATATCTTGCAAACTGGACATTAA
AACCAATTTTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATC
TTGCAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACAGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTT
ATCAGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGC
CAGAGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTT
TCAGGCGATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATTAAACAATTGCTAACCATCTTATTTGATAA
TGCTCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCG
CCGATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACG
CGTCAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGA
AGATAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCC
AAAAGTTGTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(333-442)

His Kinase A (phospho-acceptor) domain (HisKA)

(223-289)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

48.837

94.298

0.461
  ciaH Streptococcus pneumoniae Rx1

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae D39

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae R6

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae TIGR4

44.321

98.465

0.436

Multiple sequence alignment