Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   EQH24_RS10185 Genome accession   NZ_CP035256
Coordinates   1964673..1965626 (-) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain TVO_1901930     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1959673..1970626
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH24_RS10160 (EQH24_10685) - 1960434..1961057 (-) 624 WP_000932657.1 hypothetical protein -
  EQH24_RS10165 (EQH24_10690) jag 1961108..1962094 (-) 987 WP_000260027.1 RNA-binding cell elongation regulator Jag/EloR -
  EQH24_RS10170 (EQH24_10695) - 1962113..1962937 (-) 825 WP_001832473.1 membrane protein insertase YidC -
  EQH24_RS10175 (EQH24_10700) rnpA 1962912..1963283 (-) 372 WP_000739244.1 ribonuclease P protein component -
  EQH24_RS11675 - 1963300..1963431 (-) 132 WP_000768904.1 hypothetical protein -
  EQH24_RS10180 (EQH24_10705) - 1963432..1964622 (-) 1191 WP_000167753.1 acetate kinase -
  EQH24_RS10185 (EQH24_10710) comYH 1964673..1965626 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  EQH24_RS10190 (EQH24_10715) - 1965687..1966281 (-) 595 Protein_2013 class I SAM-dependent methyltransferase -
  EQH24_RS10195 (EQH24_10720) comGG/cglG 1966418..1966831 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH24_RS10200 (EQH24_10725) comGF/cglF 1966809..1967270 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH24_RS10205 (EQH24_10730) comGE/cglE 1967233..1967535 (-) 303 WP_256901086.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH24_RS10210 (EQH24_10735) comGD/cglD 1967498..1967902 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH24_RS10215 (EQH24_10740) comGC/cglC 1967895..1968161 (-) 267 WP_050129046.1 competence type IV pilus major pilin ComGC Machinery gene
  EQH24_RS10220 (EQH24_10745) - 1968163..1968420 (-) 258 WP_238101663.1 hypothetical protein -
  EQH24_RS10225 (EQH24_10750) - 1968652..1969608 (-) 957 WP_000350480.1 N-acetylmuramoyl-L-alanine amidase family protein -
  EQH24_RS10230 (EQH24_10755) - 1969612..1969944 (-) 333 WP_001186219.1 phage holin -
  EQH24_RS10235 (EQH24_10760) - 1969948..1970247 (-) 300 WP_001811580.1 hypothetical protein -
  EQH24_RS10240 (EQH24_10765) - 1970256..1970606 (-) 351 WP_000852245.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=338023 EQH24_RS10185 WP_000345126.1 1964673..1965626(-) (comYH) [Streptococcus pneumoniae strain TVO_1901930]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=338023 EQH24_RS10185 WP_000345126.1 1964673..1965626(-) (comYH) [Streptococcus pneumoniae strain TVO_1901930]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAACCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment