Detailed information NTG0337666

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EQH31_RS04630
• Genome accession: NZ_CP035249
• Coordinates: 906858..909098 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942422.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901938
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 901858..914098

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH31_RS04600 (EQH31_04895)	-	902021..902989 (+)	969	WP_000658181.1	PhoH family protein	-
EQH31_RS04605 (EQH31_04900)	-	903169..903669 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
EQH31_RS04610 (EQH31_04905)	-	903672..903998 (+)	327	Protein_927	TfoX/Sxy family protein	-
EQH31_RS04615 (EQH31_04910)	ald	904299..905410 (-)	1112	Protein_928	alanine dehydrogenase	-
EQH31_RS04620 (EQH31_04915)	-	905587..906156 (+)	570	WP_000443745.1	GNAT family N-acetyltransferase	-
EQH31_RS04625 (EQH31_04920)	comEA/celA/cilE	906224..906874 (+)	651	WP_000387352.1	helix-hairpin-helix domain-containing protein	Machinery gene
EQH31_RS04630 (EQH31_04925)	comEC/celB	906858..909098 (+)	2241	WP_000942422.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EQH31_RS04635 (EQH31_04930)	-	909278..909466 (+)	189	WP_010976492.1	hypothetical protein	-
EQH31_RS04640 (EQH31_04935)	-	909498..910085 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
EQH31_RS04645 (EQH31_04940)	-	910089..911264 (+)	1176	WP_000655940.1	hypothetical protein	-
EQH31_RS04650 (EQH31_04945)	infC	911585..912115 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
EQH31_RS04655 (EQH31_04950)	rpmI	912148..912348 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
EQH31_RS04660 (EQH31_04955)	rplT	912400..912759 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
EQH31_RS04665 (EQH31_04960)	-	912817..913197 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84696.39 Da
• Isoelectric Point: 9.4461

>NTDB_id=337666 EQH31_RS04630 WP_000942422.1 906858..909098(+) (comEC/celB) [Streptococcus pneumoniae strain TVO_1901938]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCLFIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQN
LVDSVERVRILPDTIKVNGDSLSFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=337666 EQH31_RS04630 WP_000942422.1 906858..909098(+) (comEC/celB) [Streptococcus pneumoniae strain TVO_1901938]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTATGGCTTTACTACGCCATTTT
CTCAGTATCCTATTTTGCTTTGTTGGGTTTTGTTTTTCTGCTAGTCTGCCTCTTTATCCAATTTCCTTGGAAATCAGCAG
GTAAAGTTCTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAACTTGGCAACAGAGTCAAGTGAGTCAAAAT
TTGGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGACACTATTAAGGTTAACGGTGACAGTCTGTCCTTTCGTGGTAA
GTCTGATGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACTGACC
TTCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTGACTACCAAGGCTAT
CTGAAGACTCAGGGAATTTACCAGACACTCAATATTAAAAGAATCCAGTCACTCCAAAAGGTTGGCAGTTGGGATATAGG
TGAAAACCTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGATGCACTTCCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTAGGACATCTGGACACCGATTTTGAGGAGATGAATGAGCTTTATTCCAGTTTAGGAATTATTCACCTT
TTTGCCTTGTCAGGTATGCAGGTAGGGTTTTTCATGGACGGATTTAAGAAACTACTTTTACGATTGGGCTTGACACAAGA
AAAGTTGAAGTGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGTGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGTAGACCGCTTGTCTTTGGACAACCCAATGAATGGCTTTTAATCCTATTGTTAATTTCTTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCAAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAAGCTTGATACCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTACCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae Rx1	96.917	100	0.969
comEC/celB	Streptococcus pneumoniae D39	96.917	100	0.969
comEC/celB	Streptococcus pneumoniae R6	96.917	100	0.969
comEC/celB	Streptococcus pneumoniae TIGR4	96.917	100	0.969
comEC/celB	Streptococcus mitis SK321	91.689	100	0.917
comEC/celB	Streptococcus mitis NCTC 12261	91.409	99.866	0.913
comEC	Lactococcus lactis subsp. cremoris KW2	44.399	99.33	0.441