Detailed information NTG0337619

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH32_RS09345
• Genome accession: NZ_CP035248
• Coordinates: 1815463..1816473 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901939
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1810463..1821473

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH32_RS09320 (EQH32_09820)	-	1811763..1812056 (-)	294	WP_000977368.1	hypothetical protein	-
EQH32_RS09325 (EQH32_09825)	-	1812218..1812670 (+)	453	WP_000079148.1	universal stress protein	-
EQH32_RS09330 (EQH32_09830)	-	1812705..1814093 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
EQH32_RS09335 (EQH32_09835)	-	1814159..1815121 (+)	963	WP_001124778.1	asparaginase	-
EQH32_RS09340 (EQH32_09840)	-	1815118..1815399 (-)	282	WP_001860736.1	hypothetical protein	-
EQH32_RS09345 (EQH32_09845)	ccpA	1815463..1816473 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH32_RS09350 (EQH32_09850)	-	1816898..1817497 (-)	600	WP_000866724.1	response regulator transcription factor	-
EQH32_RS09355 (EQH32_09855)	-	1817498..1818595 (-)	1098	WP_000893522.1	sensor histidine kinase	-
EQH32_RS09360 (EQH32_09860)	-	1818595..1819332 (-)	738	WP_000832833.1	ABC transporter permease	-
EQH32_RS09365 (EQH32_09865)	-	1819334..1820218 (-)	885	WP_001055990.1	ABC transporter ATP-binding protein	-
EQH32_RS09370 (EQH32_09870)	-	1820205..1820399 (-)	195	WP_000709198.1	hypothetical protein	-
EQH32_RS09375 (EQH32_09875)	-	1820396..1820602 (-)	207	WP_001818960.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=337619 EQH32_RS09345 WP_000990607.1 1815463..1816473(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901939]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=337619 EQH32_RS09345 WP_000990607.1 1815463..1816473(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901939]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGCTTAGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTAGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568