Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   EQH33_RS07725 Genome accession   NZ_CP035247
Coordinates   1554317..1556296 (-) Length   659 a.a.
NCBI ID   WP_000614557.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901940     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1549317..1561296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH33_RS07695 (EQH33_08170) - 1549412..1550686 (-) 1275 WP_000704388.1 hydroxymethylglutaryl-CoA reductase, degradative -
  EQH33_RS07700 (EQH33_08175) - 1550686..1551858 (-) 1173 WP_000151960.1 hydroxymethylglutaryl-CoA synthase -
  EQH33_RS07705 (EQH33_08180) - 1551992..1552237 (-) 246 Protein_1539 hypothetical protein -
  EQH33_RS07710 (EQH33_08185) - 1552305..1552931 (-) 627 Protein_1540 transposase family protein -
  EQH33_RS07715 (EQH33_08190) - 1552993..1553442 (-) 450 WP_000176924.1 threonine/serine exporter family protein -
  EQH33_RS07720 (EQH33_08195) - 1553444..1554202 (-) 759 WP_000392880.1 threonine/serine exporter ThrE family protein -
  EQH33_RS07725 (EQH33_08200) stkP 1554317..1556296 (-) 1980 WP_000614557.1 serine/threonine-protein kinase StkP Regulator
  EQH33_RS07730 (EQH33_08205) - 1556293..1557033 (-) 741 WP_000406247.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EQH33_RS07735 (EQH33_08210) rsmB 1557048..1558361 (-) 1314 WP_001812782.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EQH33_RS07740 (EQH33_08215) fmt 1558354..1559289 (-) 936 WP_000163698.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 72374.90 Da        Isoelectric Point: 8.9177

>NTDB_id=337524 EQH33_RS07725 WP_000614557.1 1554317..1556296(-) (stkP) [Streptococcus pneumoniae strain TVO_1901940]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEVVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIK
NPSQAVTEETYQPQAPKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKETLKKANFEIGEEKTE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTV
LKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAG
TTYDVSKPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAEGMVVEQSPRAGEKVDL
NKTRVKISIYKPKTTSATP

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=337524 EQH33_RS07725 WP_000614557.1 1554317..1556296(-) (stkP) [Streptococcus pneumoniae strain TVO_1901940]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCGGATGTCTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGGACCAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTATCTTGCGATGGAGTATGTTGCTGGACTAGACCTCAAACGCTATATCAAGGAACATTATCC
TCTTTCTAATGAAGAAGTAGTCCGTATCATGGGACAAATTCTCTTGGCTATGCGCTTGGCCCATACTCGAGGAATTGTTC
ACAGGGACTTGAAACCTCAAAATATCCTTTTGACACCAGATGGGACTGCCAAGGTCACAGACTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTCTGACCCAGACTAACTCGATGTTGGGCTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
TAAGGCGACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGTTGACAGGCCATATCCCTTATGACG
GGGATAGCGCGGTGACCATTGCCCTCCAGCATTTCCAGAAACCCCTGCCGTCCGTTATTGCAGAAAATCCATCTGTACCT
CAGGCTTTAGAAAATGTTATTATCAAGGCAACTGCTAAAAAGTTGACCAATCGCTACCGCTCGGTTTCAGAGATGTATGT
GGACTTGTCTAGTAGCTTGTCCTACAATCGTAGAAATGAAAGTAAGTTAATCTTTGATGAAACGAGCAAGGCAGATACCA
AGACCTTGCCGAAGGTTTCTCAGAGTACCTTGACATCTATTCCTAAGGTTCAAGCGCAGACAGAACACAAATCAATCAAA
AACCCAAGCCAGGCTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACATAGATTTAAGATGCGTTACCTGAT
TTTGTTGGCCAGCCTTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCCAGAACTCCTGCAACCATTGCCATTCCAG
ATGTGGCAGGTCAGACAGTTGCAGAGGCCAAGGAAACCCTCAAGAAAGCCAATTTTGAGATTGGTGAGGAGAAGACAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGCGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATTTGGTTGTCTCATCAGGCAAGCAATCTTTCCAAATTAGTAATTATGTCGGTCGGAAATCCTCTGATGTCATTGCGG
AATTAAAAGAGAAAAAAGTTCCAGATAATTTGATTAAAATTGAGGAAGAAGAGTCGAATGAGAGTGAGGCTGGAACGGTC
TTGAAGCAAAGTCTACCAGAAGGTACGACCTATGACTTGAGCAAGGCAACTCAAATTGTTTTGACAGTAGCTAAAAAAGC
TACGACGATTCAATTAGGGAACTATATTGGACGGAACTCTACAGAAGTAATCTCAGAACTCAAGCAGAAGAAGGTTCCTG
AGAATTTGATTAAGATAGAGGAAGAAGAGTCCAGCGAAAGCGAACCAGGAACGATTATGAAACAAAGTCCAGGTGCCGGA
ACGACTTATGATGTGAGTAAACCTACTCAAATTGTCTTGACAGTAGCTAAAAAAGTTACAAGTGTTGCCATGCCGAGTTA
CATTGGTTCCAGCTTGGAGTTTACTAAGAACAATTTGATTCAAATTGTTGGGATTAAGGAAGCTAATATAGAAGTTGTAG
AAGTGACGACAGCGCCTGCAGGTAGTGCAGAAGGCATGGTTGTTGAACAAAGTCCTAGAGCAGGTGAAAAGGTAGACCTC
AATAAGACTAGAGTCAAGATTTCAATCTACAAACCTAAAACAACTTCAGCTACTCCTTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(513-577)

PASTA domain (PASTA)

(582-651)

PASTA domain (PASTA)

(371-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

99.697

100

0.997
  stkP Streptococcus pneumoniae D39

99.241

100

0.992
  stkP Streptococcus pneumoniae R6

99.241

100

0.992
  stkP Streptococcus pneumoniae Rx1

99.09

100

0.991
  pknB Streptococcus mutans UA159

52.821

88.771

0.469
  stkP/pknB Streptococcus salivarius strain HSISS4

51.979

88.164

0.458

Multiple sequence alignment