Detailed information NTG0337149

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: EQH38_RS07120
• Genome accession: NZ_CP035242
• Coordinates: 1377731..1378684 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain TVO_1901947
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1372731..1383684

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH38_RS07095 (EQH38_07480)	-	1373220..1373315 (-)	96	Protein_1381	IS630 family transposase	-
EQH38_RS07100 (EQH38_07490)	-	1373729..1374070 (+)	342	Protein_1382	IS3 family transposase	-
EQH38_RS07105 (EQH38_07495)	prsA	1374187..1375128 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
EQH38_RS07110 (EQH38_07500)	-	1375195..1375908 (-)	714	WP_077141330.1	O-methyltransferase	-
EQH38_RS07115 (EQH38_07505)	pepF	1375910..1377712 (-)	1803	WP_061367457.1	oligoendopeptidase F	Regulator
EQH38_RS07120 (EQH38_07510)	coiA	1377731..1378684 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
EQH38_RS07125 (EQH38_07515)	tehB	1378757..1379617 (-)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
EQH38_RS07130 (EQH38_07520)	smpB	1379633..1380100 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
EQH38_RS07135 (EQH38_07525)	rnr	1380063..1382417 (-)	2355	WP_000654872.1	ribonuclease R	-
EQH38_RS07140 (EQH38_07530)	secG	1382519..1382752 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
EQH38_RS07145 (EQH38_07535)	rpmG	1382792..1382941 (-)	150	WP_001809104.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=337149 EQH38_RS07120 WP_000495909.1 1377731..1378684(-) (coiA) [Streptococcus pneumoniae strain TVO_1901947]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=337149 EQH38_RS07120 WP_000495909.1 1377731..1378684(-) (coiA) [Streptococcus pneumoniae strain TVO_1901947]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTGTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435