Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   EQH39_RS10025 Genome accession   NZ_CP035241
Coordinates   1968251..1968913 (-) Length   220 a.a.
NCBI ID   WP_000649974.1    Uniprot ID   A0A0F7YBW3
Organism   Streptococcus pneumoniae strain TVO_1901948     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1963251..1973913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH39_RS10000 (EQH39_10510) - 1963401..1963667 (-) 267 WP_001278167.1 Veg family protein -
  EQH39_RS10005 (EQH39_10515) dnaB 1963669..1965021 (-) 1353 WP_000852486.1 replicative DNA helicase -
  EQH39_RS10010 (EQH39_10520) rplI 1965065..1965517 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  EQH39_RS10015 (EQH39_10525) - 1965514..1967487 (-) 1974 WP_000715130.1 DHH family phosphoesterase -
  EQH39_RS10020 (EQH39_10530) hpf 1967623..1968171 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EQH39_RS10025 (EQH39_10535) comFC/cflB 1968251..1968913 (-) 663 WP_000649974.1 ComF family protein Machinery gene
  EQH39_RS10030 (EQH39_10540) comFA/cflA 1968910..1970208 (-) 1299 WP_000867605.1 DEAD/DEAH box helicase Machinery gene
  EQH39_RS10035 (EQH39_10545) - 1970264..1970899 (+) 636 WP_000395730.1 YigZ family protein -
  EQH39_RS10040 (EQH39_10550) cysK 1971184..1972104 (+) 921 WP_000029866.1 cysteine synthase A -
  EQH39_RS10045 (EQH39_10560) - 1972343..1972717 (-) 375 Protein_1958 IS66 family transposase -
  EQH39_RS10050 (EQH39_10565) - 1972690..1972998 (+) 309 Protein_1959 transposase -
  EQH39_RS10055 (EQH39_10570) tnpB 1973189..1973476 (-) 288 WP_000586646.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25169.03 Da        Isoelectric Point: 7.7116

>NTDB_id=337095 EQH39_RS10025 WP_000649974.1 1968251..1968913(-) (comFC/cflB) [Streptococcus pneumoniae strain TVO_1901948]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=337095 EQH39_RS10025 WP_000649974.1 1968251..1968913(-) (comFC/cflB) [Streptococcus pneumoniae strain TVO_1901948]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGGAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGTTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

100

100

1
  comFC/cflB Streptococcus pneumoniae D39

100

100

1
  comFC/cflB Streptococcus pneumoniae R6

100

100

1
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment