Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   EQH39_RS00215 Genome accession   NZ_CP035241
Coordinates   41753..43102 (+) Length   449 a.a.
NCBI ID   WP_000801604.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901948     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 36753..48102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH39_RS00190 (EQH39_00205) plsX 36871..37863 (+) 993 WP_000717457.1 phosphate acyltransferase PlsX -
  EQH39_RS00195 (EQH39_00210) - 37869..38102 (+) 234 WP_000659556.1 acyl carrier protein -
  EQH39_RS00200 (EQH39_00215) - 38139..38439 (+) 301 Protein_33 transposase family protein -
  EQH39_RS00205 (EQH39_00220) blpU 38642..38872 (+) 231 Protein_34 bacteriocin-like peptide BlpU -
  EQH39_RS10220 - 38875..39000 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  EQH39_RS00210 (EQH39_00225) comA 39587..41740 (+) 2154 WP_000668280.1 peptide cleavage/export ABC transporter ComA Regulator
  EQH39_RS00215 (EQH39_00230) comB 41753..43102 (+) 1350 WP_000801604.1 competence pheromone export protein ComB Regulator
  EQH39_RS00220 (EQH39_00235) purC 43272..43979 (+) 708 WP_000043305.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  EQH39_RS00225 (EQH39_00240) - 44036..47761 (+) 3726 WP_000361233.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49714.58 Da        Isoelectric Point: 5.2560

>NTDB_id=337029 EQH39_RS00215 WP_000801604.1 41753..43102(+) (comB) [Streptococcus pneumoniae strain TVO_1901948]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKEDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLINQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=337029 EQH39_RS00215 WP_000801604.1 41753..43102(+) (comB) [Streptococcus pneumoniae strain TVO_1901948]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAAAAGGAGATGAGCTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGAGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAATCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATGGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCAAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTTCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
TCTACAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

98.664

100

0.987
  comB Streptococcus pneumoniae D39

98.441

100

0.984
  comB Streptococcus pneumoniae R6

98.441

100

0.984
  comB Streptococcus pneumoniae Rx1

98.441

100

0.984
  comB Streptococcus mitis SK321

94.655

100

0.947
  comB Streptococcus mitis NCTC 12261

94.209

100

0.942
  comB Streptococcus gordonii str. Challis substr. CH1

54.889

100

0.55

Multiple sequence alignment