Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FY406_RS07610 Genome accession   NZ_CP043405
Coordinates   1512361..1513041 (+) Length   226 a.a.
NCBI ID   WP_003087804.1    Uniprot ID   A0ABN0GT77
Organism   Streptococcus ratti strain ATCC 31377     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1507361..1518041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS07595 (FY406_07595) rlmD 1508649..1510004 (+) 1356 WP_003087800.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  FY406_RS07600 (FY406_07600) - 1510089..1511021 (+) 933 WP_003087801.1 CPBP family intramembrane glutamic endopeptidase -
  FY406_RS07605 (FY406_07605) - 1511669..1512226 (+) 558 WP_225310747.1 GNAT family N-acetyltransferase -
  FY406_RS07610 (FY406_07610) ciaR 1512361..1513041 (+) 681 WP_003087804.1 response regulator transcription factor Regulator
  FY406_RS07615 (FY406_07615) - 1513035..1514198 (+) 1164 WP_003087805.1 cell wall metabolism sensor histidine kinase WalK -
  FY406_RS07620 (FY406_07620) - 1514210..1514332 (+) 123 WP_003087806.1 teichoic acid D-Ala incorporation-associated protein DltX -
  FY406_RS07625 (FY406_07625) dltA 1514346..1515884 (+) 1539 WP_003087808.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  FY406_RS07630 (FY406_07630) dltB 1515881..1517146 (+) 1266 WP_003087810.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  FY406_RS07635 (FY406_07635) dltC 1517583..1517822 (+) 240 WP_003087812.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25603.93 Da        Isoelectric Point: 5.0504

>NTDB_id=336869 FY406_RS07610 WP_003087804.1 1512361..1513041(+) (ciaR) [Streptococcus ratti strain ATCC 31377]
MRILVVEDEKGIAEAIKAILEEGHYDVDLAFDGEMGMDYILTELYDLVLLDIMLPKIDGVTVLKRVRQLGMEVPIIFLTA
KSQLEDRVAGLDLGADDYLTKPFEAEELLARIRVRTRQSSAAKVNHLKLGNVILNLDTRELTVSDHEVKLSNKEFLLMET
LLRNPKQIIPKSQLIMKVWGPLDESDYNQLEVFISFLRKKLRFLKANIAIKTTKGVGYSLEEASAC

Nucleotide


Download         Length: 681 bp        

>NTDB_id=336869 FY406_RS07610 WP_003087804.1 1512361..1513041(+) (ciaR) [Streptococcus ratti strain ATCC 31377]
ATGCGGATTCTAGTTGTTGAAGATGAGAAAGGCATTGCAGAAGCTATAAAAGCTATTTTAGAAGAGGGTCATTACGATGT
TGATTTAGCTTTTGACGGTGAAATGGGAATGGATTATATTTTAACGGAACTTTATGATTTAGTTTTGCTGGACATCATGC
TTCCCAAAATAGATGGTGTGACCGTCTTGAAGCGGGTACGTCAGCTAGGTATGGAGGTTCCTATCATTTTCCTGACAGCC
AAATCTCAGCTAGAGGACCGTGTTGCAGGGCTTGACCTAGGAGCAGACGACTACTTGACTAAGCCTTTTGAGGCGGAGGA
ATTGCTGGCGCGCATTCGTGTAAGAACCCGCCAATCATCGGCGGCCAAGGTTAATCATCTCAAGCTGGGTAATGTCATTT
TGAATTTGGATACCCGTGAGCTGACTGTGAGTGACCACGAAGTCAAACTCTCCAATAAAGAATTTCTACTCATGGAAACC
TTGTTACGCAATCCCAAGCAGATTATTCCCAAAAGCCAACTGATTATGAAAGTCTGGGGACCCTTGGATGAGTCAGACTA
CAATCAACTAGAAGTCTTCATCTCCTTCTTGCGGAAAAAGCTGCGCTTCCTCAAGGCAAATATTGCCATCAAGACCACCA
AGGGGGTTGGCTATTCTTTGGAGGAGGCTAGCGCATGCTAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)

Response regulator receiver domain (Response_reg)

(3-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae TIGR4

39.286

99.115

0.389
  ciaR Streptococcus pneumoniae D39

39.286

99.115

0.389
  ciaR Streptococcus pneumoniae R6

39.286

99.115

0.389
  ciaR Streptococcus pneumoniae Rx1

39.286

99.115

0.389
  covR Streptococcus salivarius strain HSISS4

38.938

100

0.389
  ciaR Streptococcus mutans UA159

38.393

99.115

0.381
  vicR Streptococcus mutans UA159

35.498

100

0.363

Multiple sequence alignment