Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC   Type   Regulator
Locus tag   EQH44_RS10630 Genome accession   NZ_CP035236
Coordinates   2100293..2100424 (-) Length   43 a.a.
NCBI ID   WP_061649796.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1902282     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 2095293..2105424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH44_RS10600 (EQH44_11200) - 2095646..2096188 (+) 543 WP_001158266.1 TetR/AcrR family transcriptional regulator -
  EQH44_RS10615 (EQH44_11215) - 2096549..2097946 (+) 1398 WP_001812112.1 ISNCY-like element IS1202 family transposase -
  EQH44_RS10770 - 2098019..2098144 (+) 126 WP_001258159.1 hypothetical protein -
  EQH44_RS10620 (EQH44_11220) comE 2098206..2098958 (-) 753 WP_000866075.1 competence system response regulator transcription factor ComE Regulator
  EQH44_RS10625 (EQH44_11225) comD/comD1 2098955..2100280 (-) 1326 WP_025169508.1 competence system sensor histidine kinase ComD Regulator
  EQH44_RS10630 (EQH44_11230) comC 2100293..2100424 (-) 132 WP_061649796.1 competence-stimulating peptide ComC Regulator
  EQH44_RS10640 (EQH44_11240) rlmH 2100706..2101185 (-) 480 WP_000695929.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EQH44_RS10645 (EQH44_11245) htrA 2101368..2102549 (+) 1182 WP_000681598.1 S1C family serine protease Regulator
  EQH44_RS10650 (EQH44_11250) spo0J 2102607..2103365 (+) 759 WP_000410381.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence


Protein


Download         Length: 43 a.a.        Molecular weight: 5299.18 Da        Isoelectric Point: 11.0565

>NTDB_id=336789 EQH44_RS10630 WP_061649796.1 2100293..2100424(-) (comC) [Streptococcus pneumoniae strain TVO_1902282]
MKNTVKLEQFVALKEKDLQNIQGGEMRKMNEKSFNFFNFFRRR

Nucleotide


Download         Length: 132 bp        

>NTDB_id=336789 EQH44_RS10630 WP_061649796.1 2100293..2100424(-) (comC) [Streptococcus pneumoniae strain TVO_1902282]
ATGAAAAACACAGTTAAATTGGAACAGTTTGTAGCTTTGAAGGAAAAAGACTTGCAAAATATTCAAGGTGGGGAGATGAG
GAAAATGAATGAAAAGTCCTTTAATTTCTTTAATTTCTTTAGAAGAAGATAA

Domains


Predicted by InterproScan.

(1-27)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus mitis NCTC 12261

67.442

100

0.674

  comC/comC2 Streptococcus pneumoniae A66

92.593

62.791

0.581

  comC/comC2 Streptococcus pneumoniae TIGR4

92.593

62.791

0.581

  comC/comC1 Streptococcus pneumoniae R6

92.593

62.791

0.581

  comC/comC1 Streptococcus pneumoniae G54

92.593

62.791

0.581

  comC/comC1 Streptococcus pneumoniae D39

92.593

62.791

0.581

  comC/comC1 Streptococcus pneumoniae Rx1

92.593

62.791

0.581

  comC Streptococcus mitis SK321

92.593

62.791

0.581


Multiple sequence alignment