Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   EQH44_RS00230 Genome accession   NZ_CP035236
Coordinates   44280..45629 (+) Length   449 a.a.
NCBI ID   WP_000801615.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1902282     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 39280..50629
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH44_RS00205 (EQH44_00210) plsX 39399..40391 (+) 993 WP_000717451.1 phosphate acyltransferase PlsX -
  EQH44_RS00210 (EQH44_00215) - 40397..40630 (+) 234 WP_000136449.1 acyl carrier protein -
  EQH44_RS00215 (EQH44_00220) - 40667..40967 (+) 301 Protein_36 transposase family protein -
  EQH44_RS00220 (EQH44_00225) blpU 41169..41399 (+) 231 WP_001093075.1 bacteriocin-like peptide BlpU -
  EQH44_RS10660 - 41402..41527 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  EQH44_RS00225 (EQH44_00230) comA 42114..44267 (+) 2154 WP_000668270.1 peptide cleavage/export ABC transporter ComA Regulator
  EQH44_RS00230 (EQH44_00235) comB 44280..45629 (+) 1350 WP_000801615.1 competence pheromone export protein ComB Regulator
  EQH44_RS00235 (EQH44_00240) purC 45799..46506 (+) 708 WP_000043301.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  EQH44_RS00240 (EQH44_00245) - 46563..50288 (+) 3726 WP_000361198.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49597.45 Da        Isoelectric Point: 5.3895

>NTDB_id=336722 EQH44_RS00230 WP_000801615.1 44280..45629(+) (comB) [Streptococcus pneumoniae strain TVO_1902282]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=336722 EQH44_RS00230 WP_000801615.1 44280..45629(+) (comB) [Streptococcus pneumoniae strain TVO_1902282]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCCAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTACTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCAAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGTAAAGCCAAACTCACAGCTTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

99.555

100

0.996
  comB Streptococcus pneumoniae D39

99.555

100

0.996
  comB Streptococcus pneumoniae R6

99.555

100

0.996
  comB Streptococcus pneumoniae TIGR4

99.332

100

0.993
  comB Streptococcus mitis SK321

94.878

100

0.949
  comB Streptococcus mitis NCTC 12261

94.432

100

0.944
  comB Streptococcus gordonii str. Challis substr. CH1

55.556

100

0.557

Multiple sequence alignment