Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   SEQ_RS11025 Genome accession   NC_012471
Coordinates   2251445..2252668 (+) Length   407 a.a.
NCBI ID   WP_012516520.1    Uniprot ID   A0AAW3GJZ4
Organism   Streptococcus equi subsp. equi 4047     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2246445..2257668
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEQ_RS11000 (SEQ_2234) - 2247078..2249663 (+) 2586 WP_015898718.1 YfhO family protein -
  SEQ_RS11020 (SEQ_2236) rlmH 2250755..2251234 (-) 480 WP_012678751.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SEQ_RS11025 (SEQ_2237) htrA 2251445..2252668 (+) 1224 WP_012516520.1 trypsin-like peptidase domain-containing protein Regulator
  SEQ_RS11030 (SEQ_2238) spo0J 2252788..2253561 (+) 774 WP_015898719.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 42434.01 Da        Isoelectric Point: 5.4809

>NTDB_id=33554 SEQ_RS11025 WP_012516520.1 2251445..2252668(+) (htrA) [Streptococcus equi subsp. equi 4047]
MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGATTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAAS
PAISNPYINLFGEENDTSAVQKEDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVTSRNEAGETISTNAIQTDAAINP
GNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGIGFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQ
LNIPTSVTSGVVVASTQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKVDIKLTKTT
KDLTKKQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=33554 SEQ_RS11025 WP_012516520.1 2251445..2252668(+) (htrA) [Streptococcus equi subsp. equi 4047]
GTGTTAAAATCAAAAAATATATTGAAGCCCTTATGGGTTTTAGCCATTGGATTTTTAGGGGGCTTATTAGCTGCCTTAGT
TGTTAATGGATTTAGTCAGAATTCTCTAACATCTTCAAATGCAAAGGGAGCAACGACAACAAGCAACGTCAGCTTTAATA
ATACAACTGATACAACAAAGGCTGTTAAGGTGGTTCAAGATGCTGTAGTGTCTGTTATTAACTATCAAAAGGCTGCTTCG
CCTGCCATTTCAAATCCTTACATCAATCTTTTCGGAGAAGAAAATGATACCTCAGCAGTACAAAAAGAGGACGAGCTAAG
CATACACAGTGAAGGTTCGGGTGTTGTCTACAAAAAAGAAGGTAATACTGCTTATCTTGTAACCAACAATCATGTTATTG
AGGGAGCTCAACGAATTGAAATTTTAACAGCAGACGGCTCTAAGATCGTTGGAGAACTAGTTGGTGCAGACACTTATTCT
GACCTAGCTGTTGTCAAAGTTGCTGCTGATAAAATCAAAACAATAGCCAAATTTGCAGATTCAACCAAAATTAATGTTGG
AGAGGTAGCCATTGCAATTGGTAGTCCTCTTGGAACAAAATATGCCAACTCAGTGACAGAAGGGATTGTTTCAAGTCTAA
GCCGTACAGTCACTTCAAGAAATGAGGCAGGCGAGACCATCTCAACAAATGCTATCCAAACTGATGCTGCTATCAATCCA
GGTAATTCAGGTGGACCACTCATCAATATTGAAGGCCAGGTTATTGGTATCAACTCAAGTAAAATATCCTCAACACCTAC
TGGTAGCGGCGGAGCCATTGAGGGAATTGGCTTTGCTATTCCATCAAGCGATGTTGTCACCATTATTAACCAACTAGAGT
CTAACGGAGCTGTTATCAGACCAGCCTTAGGCATTACAATGGTAAACTTAAGTAATCTATCAACCAATGCATTGATTCAA
TTGAATATTCCAACAAGCGTTACCAGCGGTGTTGTCGTAGCCTCTACTCAAGATGGCATGCCTGCTCTTGGTAAATTGGA
GCAGTATGATGTCATTACTGAGGTTGACGGTAAAGAAGTCAGCTCAATTAGTGACCTACAAAGTGTCTTATATAGTCATG
AGATTAACGACACCATTAAGGTAACCTTCTACAGAGGAACTGCTAAGAAGAAAGTTGACATCAAATTAACAAAAACAACT
AAGGATCTAACTAAAAAGCAGTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(112-257)

PDZ domain (PDZ_2)

(301-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.275

100

0.614
  htrA Streptococcus gordonii str. Challis substr. CH1

57.855

98.526

0.57
  htrA Streptococcus mitis NCTC 12261

54.66

97.543

0.533
  htrA Streptococcus pneumoniae Rx1

53.634

98.034

0.526
  htrA Streptococcus pneumoniae D39

53.634

98.034

0.526
  htrA Streptococcus pneumoniae R6

53.634

98.034

0.526
  htrA Streptococcus pneumoniae TIGR4

53.634

98.034

0.526

Multiple sequence alignment