Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   SEQ_RS07665 Genome accession   NC_012471
Coordinates   1581624..1582334 (-) Length   236 a.a.
NCBI ID   WP_012515994.1    Uniprot ID   -
Organism   Streptococcus equi subsp. equi 4047     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1576624..1587334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEQ_RS11345 - 1578011..1579384 (-) 1374 Protein_1470 IS3 family transposase -
  SEQ_RS07655 (SEQ_1575) vicX 1579466..1580275 (-) 810 WP_042357090.1 MBL fold metallo-hydrolase Regulator
  SEQ_RS07660 (SEQ_1576) vicK 1580279..1581631 (-) 1353 WP_012679848.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SEQ_RS07665 (SEQ_1577) vicR 1581624..1582334 (-) 711 WP_012515994.1 response regulator YycF Regulator
  SEQ_RS07670 (SEQ_1578) - 1582533..1583552 (-) 1020 WP_012679849.1 DUF3114 domain-containing protein -
  SEQ_RS07675 (SEQ_1579) - 1583598..1584860 (-) 1263 WP_012679850.1 AMP-binding protein -
  SEQ_RS07680 (SEQ_1580) - 1584850..1585965 (-) 1116 WP_012679851.1 acetyl-CoA C-acyltransferase -
  SEQ_RS07685 (SEQ_1581) - 1585962..1586501 (-) 540 WP_042357092.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26981.84 Da        Isoelectric Point: 4.9038

>NTDB_id=33530 SEQ_RS07665 WP_012515994.1 1581624..1582334(-) (vicR) [Streptococcus equi subsp. equi 4047]
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKAYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=33530 SEQ_RS07665 WP_012515994.1 1581624..1582334(-) (vicR) [Streptococcus equi subsp. equi 4047]
ATGAAGAAAATACTGATTGTTGATGATGAAAAGCCGATTTCTGATATCATTAAATTTAATCTGACAAAGGAAGGCTATGA
TACGGTCACAGCATTTGATGGCAAAGAGGCCGTTGCAGTCTTTGAAGAGGAAAAGCCAGATTTGATTATTTTGGATTTGA
TGCTTCCTGAATTAGATGGCCTTGAGGTAGCCAAGGAAATCCGCAAGACCAGCCATATTCCTATCATCATGCTATCTGCT
AAGGATAGCGAATTTGATAAGGTGATTGGACTTGAAATAGGGGCCGATGATTATGTGACTAAGCCCTTTTCAAATCGTGA
GCTGCTGGCGCGTGTCAAGGCACATTTGCGTCGGACAGAGACTATTGAGACAGCAGTAGCCGAAGAAAATGCCTCCTCAG
GCTCTCAGGAGCTAACCATCGGCAATCTACAGATTTTACCAGATGCCTTTATCGCTAAAAAGCATGGTCAAGAGGTTGAG
CTGACCCATCGTGAGTTTGAATTGCTGCATCATCTGGCAAACCATATCGGACAGGTCATGACACGTGAGCATTTGCTTGA
GACCGTATGGGGCTACGATTATTTTGGCGATGTTCGAACCGTTGACGTTACTATCCGTCGCCTGCGCGAAAAAATAGAGG
ATACACCGAGTCGTCCAGAGTATATTTTGACAAGACGTGGTGTTGGGTACTACATGAAGGCTTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.983

100

0.89
  micA Streptococcus pneumoniae Cp1015

78.112

98.729

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

38.034

99.153

0.377

Multiple sequence alignment