Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SPJ_RS10195 Genome accession   NC_012466
Coordinates   1913206..1913508 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae JJA     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1908206..1918508
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPJ_RS10165 (SPJ_2048) rnpA 1908893..1909264 (-) 372 WP_000739246.1 ribonuclease P protein component -
  SPJ_RS13615 (SPJ_2049) - 1909281..1909412 (-) 132 WP_000768904.1 hypothetical protein -
  SPJ_RS10170 (SPJ_2050) - 1909413..1910603 (-) 1191 WP_000167771.1 acetate kinase -
  SPJ_RS10175 (SPJ_2051) comYH 1910654..1911607 (-) 954 WP_000345122.1 class I SAM-dependent methyltransferase Machinery gene
  SPJ_RS10180 (SPJ_2052) - 1911668..1912255 (-) 588 WP_000679779.1 class I SAM-dependent methyltransferase -
  SPJ_RS10185 (SPJ_2053) comGG/cglG 1912358..1912804 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  SPJ_RS10190 (SPJ_2054) comGF/cglF 1912782..1913243 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPJ_RS10195 (SPJ_2055) comGE/cglE 1913206..1913508 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPJ_RS10200 (SPJ_2056) comGD/cglD 1913471..1913875 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPJ_RS10205 (SPJ_2057) comGC/cglC 1913868..1914194 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  SPJ_RS10210 (SPJ_2058) comGB/cglB 1914196..1915212 (-) 1017 WP_078134418.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPJ_RS10215 (SPJ_2059) comGA/cglA/cilD 1915160..1916101 (-) 942 WP_000249573.1 competence type IV pilus ATPase ComGA Machinery gene
  SPJ_RS10220 (SPJ_2060) - 1916177..1916542 (-) 366 WP_000286415.1 DUF1033 family protein -
  SPJ_RS10225 (SPJ_2061) - 1916693..1917751 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=33185 SPJ_RS10195 WP_000413382.1 1913206..1913508(-) (comGE/cglE) [Streptococcus pneumoniae JJA]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=33185 SPJ_RS10195 WP_000413382.1 1913206..1913508(-) (comGE/cglE) [Streptococcus pneumoniae JJA]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment