Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   EHW89_RS02625 Genome accession   NZ_CP034543
Coordinates   524010..526160 (-) Length   716 a.a.
NCBI ID   WP_126466597.1    Uniprot ID   A0A3Q9EXX5
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 519010..531160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS02605 (EHW89_02605) cvfB 519715..520569 (+) 855 WP_126466595.1 RNA-binding virulence regulatory protein CvfB -
  EHW89_RS02610 (EHW89_02610) holA 520650..521687 (+) 1038 WP_021001445.1 DNA polymerase III subunit delta -
  EHW89_RS02615 (EHW89_02615) - 521758..522363 (+) 606 WP_003025442.1 superoxide dismutase -
  EHW89_RS02620 (EHW89_02620) - 522638..523999 (-) 1362 WP_126466596.1 bacteriocin secretion accessory protein -
  EHW89_RS02625 (EHW89_02625) comA/nlmT 524010..526160 (-) 2151 WP_126466597.1 peptide cleavage/export ABC transporter Regulator
  EHW89_RS02630 (EHW89_02630) - 526442..527497 (+) 1056 WP_126466598.1 serine hydrolase -
  EHW89_RS02635 (EHW89_02635) - 527634..528320 (+) 687 WP_126466599.1 Crp/Fnr family transcriptional regulator -
  EHW89_RS02640 (EHW89_02640) arcA 528630..529859 (+) 1230 WP_126466600.1 arginine deiminase -
  EHW89_RS02645 (EHW89_02645) argF 529883..530899 (+) 1017 WP_126466601.1 ornithine carbamoyltransferase -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 80711.03 Da        Isoelectric Point: 9.2383

>NTDB_id=331772 EHW89_RS02625 WP_126466597.1 524010..526160(-) (comA/nlmT) [Streptococcus periodonticum strain KCOM 2412]
MNFKKSFVPQIDARDCGVAALASIAKYYGSNYSLAHLRELAKTDKEGTTALGIVKAAKEMDFETRPIQADMTLFDTEELP
YPFIVHVNKNGKLQHYYVVYKNEKKHLLISDPDPTVKITKISKEQFTKEWTGVAIFLAPKPNYKPHKDKKNGLASFLPLI
FKQRSLIFYIVLASLLVTFINIVGSYYLQSVLDEYIPNQMKSTLGIISIGLIIAYILQQMMSFSRDYLLTVLSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLSIVMIVGSVLLLQNAHLFLLTLLAIPIYALI
IFAFMNPFEKMNNDVMQSNAMVNSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKTFKLSKYSIMQAALKQGAQFI
LNVIILWVGASLAMSQKISIGQLITFNALLSYFTNPLESIINLQTKLQSAKVANHRLNEVYLVESEFKTKQVLTEKNFLA
GDITFHNVSYKYGFGRDTLSDISLTIKKGDKISLVGISGSGKTTLAKMIVYFYEPYQGQIRLNGNDLKTIDKKVLRQYIN
YLPQQAYIFSGSILDNLTLGADQTVSQSDILRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMKFPDKTIIFVAHRLSISKRTNQIIVLDQGKVIETGSHTELIERKGFYYHLFNK

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=331772 EHW89_RS02625 WP_126466597.1 524010..526160(-) (comA/nlmT) [Streptococcus periodonticum strain KCOM 2412]
GTGAATTTTAAAAAATCGTTTGTTCCACAAATAGATGCTAGAGATTGTGGTGTTGCTGCTCTGGCTTCCATTGCTAAATA
CTATGGTTCAAATTATTCTTTAGCACACTTGAGAGAGCTCGCAAAGACAGACAAAGAAGGGACAACTGCACTTGGAATTG
TCAAAGCAGCAAAAGAAATGGACTTTGAAACCCGACCAATCCAAGCAGACATGACATTGTTTGATACAGAAGAGCTTCCC
TATCCTTTCATCGTACATGTCAACAAAAACGGTAAGCTCCAGCATTATTATGTCGTTTATAAAAACGAAAAAAAGCACTT
GCTTATCAGTGATCCTGATCCAACTGTCAAAATAACTAAGATTAGCAAAGAACAATTTACTAAAGAATGGACAGGTGTTG
CTATCTTTCTCGCACCAAAACCTAACTATAAACCTCATAAGGATAAGAAAAATGGACTTGCTAGCTTTTTACCACTCATC
TTTAAACAGCGTTCTTTGATTTTTTATATTGTCTTAGCTAGTTTGCTCGTGACCTTCATCAACATTGTTGGCTCCTATTA
TCTGCAAAGTGTTTTGGACGAATACATCCCAAATCAGATGAAATCAACTCTTGGGATTATTTCGATTGGACTTATCATTG
CCTACATCTTACAGCAAATGATGAGTTTTTCAAGAGACTACCTGCTAACAGTGCTCAGTCAACGATTAACAATTGATGTG
ATTTTGTCTTATATTCGGCATATTTTTGAATTGCCAATGTCCTTTTTTGCGACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCCAACTCCATTATTGATGCTCTAGCTTCAACTATCCTGTCTCTCTTTCTTGATTTGTCCATTGTGATGA
TTGTCGGTAGTGTTCTTTTACTGCAAAATGCCCATCTCTTTTTACTCACTTTACTTGCAATTCCTATCTACGCTCTCATT
ATTTTTGCTTTTATGAACCCTTTTGAAAAAATGAACAACGATGTTATGCAAAGCAATGCTATGGTGAATTCTGCTATTAT
CGAAGATATCAATGGAATTGAAACCATTAAATCTTTAACTAGCGAAGAAAGTCGTTACCAAAAAATTGATAGCGAGTTTG
TTGATTATCTGGATAAAACTTTCAAATTAAGTAAATATTCCATTATGCAGGCAGCGCTCAAACAAGGAGCACAATTTATT
TTGAATGTGATTATTCTCTGGGTCGGAGCCTCTTTGGCTATGTCTCAAAAAATTTCGATTGGACAACTGATTACTTTCAA
TGCACTCCTTTCGTATTTTACAAACCCGCTTGAAAGTATCATCAATCTTCAAACCAAACTGCAATCAGCTAAAGTTGCCA
ATCATCGACTGAATGAAGTTTATCTGGTAGAATCTGAATTCAAAACCAAACAAGTCCTTACGGAGAAAAATTTCTTAGCT
GGTGATATTACTTTTCATAACGTCTCCTATAAATATGGCTTTGGACGAGATACTTTATCAGATATTAGTTTAACTATCAA
GAAGGGAGATAAAATCAGTCTTGTCGGTATTAGCGGTTCGGGAAAAACAACACTTGCTAAGATGATTGTTTATTTTTATG
AGCCTTATCAAGGACAAATTCGCCTCAATGGAAATGACCTCAAGACAATTGATAAGAAAGTTCTTCGGCAATATATCAAC
TACTTACCTCAGCAAGCTTACATCTTTAGTGGTTCCATTCTAGACAACCTCACATTAGGAGCCGATCAAACAGTTTCCCA
ATCAGATATTCTTCGTGCCTGTGAAATTGCAGAAATTCGTTCAGATATCGAACAAATGCCCATGGGATACCAGACAGAAT
TGTCTGACGGAGCTGGATTATCTGGTGGGCAAAAACAGCGAATCGCACTTGCACGCGCTCTGCTGACGAAATCTCCCATT
CTCATTTTAGATGAAGCAACGAGTGGATTAGATGTTCTAACAGAGAAAAAAGTCATTGATAATCTCATGAAATTCCCCGA
CAAAACCATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGTACAAATCAGATTATCGTCCTTGACCAAGGAAAAG
TGATTGAAACTGGTTCTCATACTGAATTGATAGAAAGAAAAGGTTTTTATTATCATCTATTTAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(499-648)

Peptidase C39 family (Peptidase_C39)

(5-141)

ABC transporter transmembrane region (ABC_membrane)

(167-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3Q9EXX5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.496

99.022

0.718
  comA Streptococcus mitis NCTC 12261

67.041

99.581

0.668
  comA Streptococcus gordonii str. Challis substr. CH1

66.527

100

0.666
  comA Streptococcus mitis SK321

66.76

99.581

0.665
  comA Streptococcus pneumoniae D39

66.339

99.581

0.661
  comA Streptococcus pneumoniae Rx1

66.339

99.581

0.661
  comA Streptococcus pneumoniae R6

66.339

99.581

0.661
  comA Streptococcus pneumoniae TIGR4

65.83

100

0.659

Multiple sequence alignment